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. 2023 May 23;14:1195149. doi: 10.3389/fendo.2023.1195149

Figure 4.

Figure 4

Identification of the core targets for YNJ against DCM. (A) The PPI network of DCM-related targets (2,981 nodes and 70,524 edges). (B) The PPI network of YNJ-related targets (10,601 nodes and 219,193 edges). (C) Intersection of PPI networks of YNJ putative targets and DCM-related targets (2,695 nodes and 68,380 edges). (D) PPI network of important targets obtained with the screening criteria of DC > 64 (666 nodes and 26,919 edges) from (C). (E) Core–target PPI network of YNJ against DCM obtained with the screening criteria of DC >101, BC > 0.00074373, and CC > 0.463790583 (204 nodes and 5,729 edges) from (D). BC, betweenness centrality; CC, closeness centrality; DC, degree centrality.