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Picro-Sirius red (PSR) staining for collagen deposition in the myocardium. (A) PSR staining to detected collagen content and fibrosis in the left ventricle (400×). (B) Calculation of PSR-positive area as displayed by CVF. Data are presented as mean ± SD. **p < 0.01 vs. the normal control group; ## p < 0.01 vs. the DM group.
