TABLE 4.
Cell populations from flow cytometry for untreated tumors of the various models.
| Model/Cell population | 4T1 OT | 4T1 SC | CMT 167 OT | CMT 167 SC | KPCY SC | MC38 SC |
|---|---|---|---|---|---|---|
| CD3+ T cells | 3.9 ± 5.3 | 5.8 ± 1.3 | 7.3 ± 2.5 | 13.9 ± 5.1 | 10.9 ± 6.8 | 8.4 ± 1.5 |
| CD8+ T cells | 0.9 ± 1.4 | 2.0 ± 1.3 | 2.7 ± 1.2 | 8.6 ± 4.1 | 8.0 ± 6.9 | 5.6 ± 1.4 |
| CD4+ T cells | 2.6 ± 3.8 | 3.3 ± 0.8 | 3.6 ± 1.2 | 3.5 ± 0.9 | 2.4 ± 0.4 | 2.1 ± 0.3 |
| NK cells | 0.3 ± 0.5 | 0.4 ± 0.2 | 2.8 ± 0.8 | 3.5 ± 0.5 | 2.7 ± 0.4 | 10.0 ± 2.2 |
| B cells | 6.5 ± 6.0 | 2.1 ± 1.7 | 1.9 ± 1.3 | 0.4 ± 0.2 | 2.0 ± 0.4 | 2.8 ± 1.6 |
| MHCII high macrophages | 4.7 ± 1.8 | 8.4 ± 2.7 | 0.5 ± 0.3 | 4.1 ± 1.1 | 1.2 ± 0.5 | 6.6 ± 2.9 |
| MHCII low macrophages | 7.0 ± 3.0 | 7.6 ± 3.1 | 1.1 ± 0.8 | 5.5 ± 1.8 | 17.6 ± 2.9 | 14.6 ± 6.5 |
| Other myeloid cells | 16.2 ± 5.2 | 11.3 ± 5.1 | 8.1 ± 3.8 | 14.7 ± 2.1 | 29.6 ± 6.6 | 17.0 ± 6.4 |
| Other immune cells a | 5.5 ± 2.7 | 2.8 ± 2.1 | 6.0 ± 1.8 | 3.5 ± 1.3 | 5.5 ± 1.6 | 11.5 ± 5.4 |
| Other (non‐immune) cells. | 56.3 ± 8.8 | 62.1 ± 4.9 | 73.3 ± 10.4 | 56.0 ± 9.3 | 30.9 ± 4.2 | 30.0 ± 9.8 |
a
Includes CD3+CD4−CD8− T cells.