TABLE 5.
Summary of the effect of PD‐1 treatment. Time to reach endpoint is displayed for each tumor model, along with number of animals in complete remission per group.
| Time to reach endpoint | Complete remission | Effect on immune landscape | |
|---|---|---|---|
| 4T1 OT | 14 days | 0/5 | No changes |
| 4T1 SC | 10 days | 0/5 | Reduced density of T cells from FCM |
| CMT 167 OT | 15 days | 0/5 | No changes in FCM (increased T cells in CLSM) |
| CMT 167 SC | 18 days | 0/5 | Increased density of myeloid cells from FCM |
| KPCY SC | 15 days | 0/5 | No changes in FCM (increased T cells in CLSM) |
| MC38 SC | 17 days | 3/5 | Increased density of T cells and B cells in FCM |