Table 4.
Hemodynamic outcomes
| Outcomes∗ | Baseline | 30 d echo | p value† (Δ baseline to 30 d) | 1 y echo | p value† (Δ baseline to 1 y) |
|---|---|---|---|---|---|
| Mean gradient, mm Hg | 39.1 ± 18.2 (95) | 22.5 ± 8.8 (94) | <0.0001 | 19.7 ± 7.6 (86) | <0.0001 |
| Peak gradient, mm Hg | 65.2 ± 28.0 (95) | 39.0 ± 14.3 (94) | <0.0001 | 34.5 ± 12.8 (86) | <0.0001 |
| Aortic valve area, cm2 | 1.1 ± 0.5 (92) | 1.3 ± 0.3 (92) | <0.0001 | 1.4 ± 0.3 (81) | <0.0001 |
| Left ventricular ejection fraction, % | 59.4 ± 10.6 (95) | 58.1 ± 10.6 (92) | 0.12 | 60.8 ± 9.6 (80) | 0.15 |
| Dimensionless velocity index | 0.25 ± 0.10 (93) | 0.31 ± 0.06 (89) | <0.0001 | 0.32 ± 0.06 (80) | <0.0001 |
∗
All values presented as mean ± SD (n). Echocardiography was not available for all patients with follow-up through 1 year. Of available echocardiography, not all hemodynamic outcomes were evaluable. The 3 patients with explanted valves were censored through 1 year.
†
p values from paired t-tests.