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Structural analysis of the FXR-DBD/RXR-DBD/IR1 complex. A: Overall structure of the FXR-DBD/RXR-DBD/IR1 complex. The FXR-DBD and RXR-DBD molecules are colored magenta and chartreuse, respectively. The DNA is colored orange. B: DNA recognition by the FXR-DBD helix H1. C: DNA recognition by the RXR-DBD helix H1. Black dashed lines are hydrogen bonds.
