TABLE 1.

Differentially abundant metabolites in patients with unfavourable outcomes compared to favourable outcomes across all samples.

	log2(FC)	raw.pval
Pre‐surgery – UWMS
Indoline‐2‐carboxylate	−2.9953	0.0212
Cytosine	−1.8178	0.0333
2‐Ketobutyrate	−3.0748	0.0433
Adenosine 3‐5‐cyclic monophosphate	2.4282	0.0458
3‐Hydroxy‐dl‐kynurenine	3.3036	0.0483
Pre‐surgery – rinse
l‐Dihydroorotic acid	6.9348	0.0391
dl‐Valine (D8)	−2.6159	0.0447
Pre‐surgery – plasma
2‐4‐Quinolinediol	−2.1424	0.0004
Folinic acid	6.8334	0.0008
S‐2‐Aminoethyl‐l‐cysteine	0.87297	0.0318
4‐Hydroxy‐l‐glutamic acid	−5.4118	0.0341
Oxamic acid	−1.3963	0.0344
Galactonic acid	−2.3856	0.0409
Post‐surgery – UWMS
4‐Hydroxybenzoic acid	−1.492	0.0022
Uridine 5‐diphosphate	7.2527	0.0022
L‐Arabinose	−2.373	0.0303
Post‐surgery – rinse
O‐Phosphorylethanolamine	−6.3571	0.0231
Thymidine	−8.088	0.0349
beta‐Nicotinamide mononucleotide	9.4645	0.0379
Post‐surgery – plasma
L‐Gluthathione (oxidised)	−3.6732	0.0042
Mevalonic acid 5‐phosphate	−3.9025	0.0069
Folinic acid	−1.7127	0.0155
4‐Quinolinol	−4.3469	0.0165
beta‐Nicotinamide mononucleotide	−2.1142	0.0191
5‐Methoxytryptamine	−5.4377	0.0203
D‐Fructose 1,6‐biphosphate	−2.2578	0.0251
cis‐Aconitic acid	2.602	0.0332
2‐3‐Dihydroxybenzoic acid	−1.7134	0.0344
d‐Xylulose‐5‐phosphate	−1.354	0.0371

Abbreviation: FC, fold change.