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. 2023 Feb 16;12(10):11049–11072. doi: 10.1002/cam4.5489

TABLE 3.

Delivery of TAM‐specific nucleic acid therapeutics in BC

Therapeutic agents Delivery systems Target genes Tumor cell lines References
siCCL18 NP‐180 CCL18 MDA‐MB‐231 169
siCCR2 CNP/siCCR2 CCR2 4T1 170
siMIF Glucan‐based siRNA carrier MIF MDA‐MB‐231/ 4T1 171
siVEGF + siPIGF PEG=MT/PC/siVEGF siPIGF NPs VEGF and PIGF 4T1 172
VEGF inhibitor + siMED1 MT/PC/siV‐D NPs VEGF and MED1 4T1 173
CRISPR‐RICTOR CRISPR‐RICTOR‐Liposomes RICTOR 4T1 174
miR‐125b RLS/MNPs/miR‐125b IRF4 4T1 176