Table 3.
Univariate and multivariate logistic regression analyses of risk factors for mortality
| Variables | Univariate analysis Odds ratio (95%CI) | P | Multivariate analysis Odds ratio (95%CI) | P |
|---|---|---|---|---|
| Age, years, IQR | 1.03(1.02–1.04) | < 0.001 | 1.02(1.00-1.04) | 0.012 |
| Sex (male), n(%) | 0.78(0.58–1.04) | 0.090 | ||
| BMI, kg/m2, IQR | 0.56(0.94–1.02) | 0.348 | ||
| Etiology, n(%) | ||||
| Biliary | Ref | Ref | ||
| Hyperlipidemic | 0.66(0.48–0.90) | 0.008 | 1.0(0.52–1.81) | 0.919 |
| Alcoholic | 1.03(0.57–1.88) | 0.926 | 0.70(0.36–1.35) | 0.284 |
| Other | 1.14(0.67–1.95) | 0.627 | 1.0(0.42–2.34) | 0.991 |
| Hypertension, n(%) | 1.33(0.97–1.82) | 0.080 | ||
| Diabetes mellitus, n(%) | 1.09(0.73–1.62) | 0.672 | ||
| Laboratory data at admission, IQR | ||||
| White blood count, × 109/L | 1.02(0.99–1.05) | 0.090 | ||
| Hematocrit, % | 0.99(0.97-1.00) | 0.116 | ||
| Serum albumin, g/L | 0.92(0.89–0.95) | < 0.001 | 1.03(0.99–1.08) | 0.165 |
| Serum urea, mmol/L | 1.13(1.11–1.17) | < 0.001 | 1.08(1.04–1.12) | < 0.001 |
| Serum creatinine, µmol/L | 1.01(1.00-1.01) | < 0.001 | 1.00(0.99-1.00) | 0.331 |
| Serum calcium, mmol/L | 0.19(0.12–0.31) | < 0.001 | 0.27(0.14–0.50) | < 0.001 |
| Serum albumin min, g/L | 0.90(0.87–0.93) | < 0.001 | 0.93(0.89–0.97) | 0.002 |
| SIRS score ≥ 2, n(%) | 1.47(1.01–2.14) | 0.045 | 1.16(0.75–1.80) | 0.506 |
| APACHE≥score ≥ 15, n(%) | 3.12(2.26–4.3) | < 0.001 | 1.73(1.19–2.51) | 0.004 |
IQR, Inter Quartile Range; BMI, Body Mass Index; Serum albumin min, the lowest albumin level within 1 week after admission; SIRS, Systemic Inflammatory Response Syndrome; APACHE, Acute Physiology and Chronic Health Evaluation