Table 4.
Baseline situation of the two groups with and without albumin infusions before and after PSM analysis in hypoalbuminemia patients
| Variables | Before Matching | After Matching | ||||
|---|---|---|---|---|---|---|
| With albumin infusions |
Without albumin infusions |
P | With albumin infusions |
Without albumin infusions |
P | |
| (N = 423) | (N = 146) | (N = 130) | (N = 130) | |||
| Age, years, IQR | 52.0(21.0) | 55.0(21.0) | 0.171 | 53.0(19.0) | 55.0(21.0) | 0.634 |
| Sex (male), n(%) | 249(58.9) | 80(54.8) | 0.390 | 73(56.2) | 69(53.1) | 0.618 |
| BMI, kg/m2, IQR | 24.1(3.6) | 23.9(4.3) | 0.399 | 24.1(3.5) | 23.9(4.5) | 0.741 |
| Etiology, n(%) | 0.348 | 0.479 | ||||
| Biliary | 210(49.6) | 84(57.5) | 68(52.3) | 79(60.8) | ||
| Hyperlipidemia | 157(37.1) | 44(30.1) | 45(34.6) | 36(27.7) | ||
| Alcoholic | 23(5.4) | 9(6.2) | 8(6.2) | 9(6.9) | ||
| Other | 33(7.8) | 9(6.2) | 9(6.9) | 6(4.6) | ||
| Hypertension, n(%) | 116(27.4) | 35(24.0) | 0.416 | 32(24.6) | 28(21.5) | 0.556 |
| Diabetes mellitus, n(%) | 59(13.9) | 17(11.6) | 0.480 | 14(10.8) | 13(10.0) | 0.839 |
| Laboratory data at admission, IQR | ||||||
| White blood count, × 109/L | 14.0(7.8) | 14.1(6.3) | 0.850 | 14.0(8.0) | 14.1(6.3) | 0.730 |
| Hematocrit, % | 43.2(10.8) | 43.4(12.6) | 0.786 | 43.1(9.4) | 43.0(12.3) | 0.978 |
| Serum albumin, g/L | 30.0(5.8) | 31.8(7.0) | 0.001 | 31.5(7.3) | 31.7(7.3) | 0.762 |
| Serum urea, mmol/L | 9.4(8.1) | 7.7(7.2) | 0.031 | 7.8(5.4) | 7.6(6.2) | 0.833 |
| Serum creatinine, µmol/L | 100.8(139.1) | 83.4(78.6) | 0.027 | 82.8(82.1) | 80.5(60.1) | 0.610 |
| Serum calcium, mmol/L | 1.7(0.4) | 1.9(0.4) | 0.003 | 1.8(0.4) | 1.9(0.3) | 0.974 |
| Serum albumin min, g/L | 27.0(4.0) | 28.0(3.1) | 0.002 | 27.4(3.0) | 28.0(3.0) | 0.168 |
| SIRS score ≥ 2, n(%) | 357(84.4) | 109(74.7) | 0.008 | 97(74.6) | 98(75.4) | 0.886 |
| APACHE≥score ≥ 15, n(%) | 109(25.8) | 24(16.4) | 0.022 | 27(20.8) | 22(16.9) | 0.428 |
| IPN, n(%) | 92(21.7) | 7(4.8) | < 0.001 | 6(4.6) | 7(5.4) | 0.776 |
| Persistent multiple organ failure, n(%) | 149(35.2) | 34(23.3) | 0.008 | 27(20.8) | 26(20.0) | 0.878 |
| Persistent multiple organ failure, n(%) | ||||||
| Respiratory | 380(89.8) | 135(92.5) | 0.350 | 124(95.4) | 123(94.6) | 0.776 |
| Renal | 137(32.4) | 23(15.8) | < 0.001 | 20(15.4) | 18(13.8) | 0.726 |
| Cardiovascular | 78(18.4) | 26(17.8) | 0.865 | 17(13.1) | 17(13.1) | 1.000 |
| Mechanical ventilation, n(%) | 227(53.7) | 37(25.3) | < 0.001 | 36(27.7) | 34(26.2) | 0.780 |
| Hemofiltration, n(%) | 76(18.0) | 11(7.5) | 0.003 | 11(8.5) | 8(6.2) | 0.475 |
IQR, Inter Quartile Range; BMI, Body Mass Index; Serum albumin min, the lowest albumin level within 1 week after admission; SIRS, Systemic Inflammatory Response Syndrome; APACHE, Acute Physiology and Chronic Health Evaluation; IPN, Infected Pancreatic Necrosis