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. 2023 Jun 5;23:510. doi: 10.1186/s12885-023-11000-3

Table 2.

Treatment and Outcome characteristics of uterine sarcoma patients stratified on the histological type (n = 40)

Characteristics All patients (n = 40) u-LMS
(n = 16)
HGESS
(n = 10)
LGESS
(n = 8)
Other histologic subtypes
(n = 6)
p-value
Primary surgery type, n(%)
 TAH + BSO 12 (30.0) 6 (50.0) 3 (25.0) 2 (16.67) 1 (8.33)
 TAH + BSO + PLND 15 (37.50) 3 (20.0) 5 (33.33) 4 (26.67) 3 (20.0) 0.045
 TAH + BS + ovarian conservation 7 (17.50) 6 (85.71) 1 (14.29) 0 (0.0) 0 (0.0)
 Myomectomy 3 (7.50) 1 (33.33) 0 (0.0) 2 (66.67) 0 (0.0)
 Surgery not done 3 (7.50) 0 (0.0) 1 (33.33) 0 (0.0) 2 (66.67)
Residual disease after primary surgery, n(%)
 Present 8 (21.62) 6 (75.0) 2 (25.0) 0 (0.0) 0 (0.0) 0.128
 Absent 29 (78.38) 10 (34.48) 7 (24.14) 8 (27.59) 4 (13.79)
Adjuvant chemotherapy received, n(%)
 Yes 24 (60.0) 7 (29.17) 6 (25.0) 5 (20.83) 6 (25.0) 0.123
 No 16 (40.0) 9 (56.25) 4 (25.0) 3 (18.75) 0 (0.0)
Chemotherapeutic regimen, n(%)
 Ifosfamide 1 (4.17) 1 (100.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Doxorubicin 2 (8.33) 1 (50.0) 0 (0.0) 0 (0.0) 1 (50.0) 0.760
 Doxorubicin + Ifosfamide 5 (20.83) 2 (40.00) 2 (40.00) 1 (20.0) 0 (0.0)
 Gemcitabine + Docetaxel 16 (66.67) 5 (31.25) 6 (37.5) 1 (6.25) 4 (25.0)
Number of Cycles received n (%)
 3 5 (20.83) 1 (20.0) 2 (40.0) 0 (0.0) 2 (40.0)
 4 13 (54.17) 7 (53.85) 3 (23.08) 2 (15.38) 1 (7.69)
 6 6 (25.0) 1 (16.67) 3 (50.0) 0 (0.0) 2 (33.33) 0.311
Adjuvant Radiation Therapy, n(%)
 Yes 9 (22.50) 4 (44.44) 2 (22.22) 2 (22.22) 1 (11.11) 0.971
 No 31 (77.50) 12 (38.71) 8 (25.81) 6 (19.35) 5 (16.13)
Hormonal therapy, n(%)
 Yes 5 (12.50) 0 (0.0) 2 (40.0) 3 (60.0) 0 (0.0) 0.042
 No 35 (87.50) 16 (45.71) 8 (22.86) 5 (14.29) 6 (17.14)
Recurrences, n(%)
 Yes 18 (45.0) 5 (27.78) 4 (22.22) 5 (27.78) 4 (22.22) 0.327
 No 22(55.0) 11 (50.0) 6 (27.27) 3 (13.64) 2 (9.09)
Follow-up, n(%)
 Alive with disease 12(30.0) 4 (33.33) 2(16.67) 5 (41.67) 1 (8.33)
 Alive with remission 22 (55.0) 11(50.0) 6 (27.27) 3 (13.64) 2 (9.09) 0.049
 Died 6 (15.0) 1(16.67) 2(33.33) 0 (0.0) 3 (50.0)