Table 1.

Mitochondrial concentrations and dissociation constants of select metabolites that bind to human MCM•cob(II)alamin (25, 26)

Metabolite	Kd (µM)	Mitochondrial concentration
ATP	30 ± 5 µM	8.0 ± 2.6 mM
ADP	44 ± 4.2 µM	6.0 ± 1.7 mM
5′-dAdo	4.2 ± 2.1 µM	NA*
CoA	118 ± 13 µM	2-5 mM
M-CoA	24.2 ± 6.2 µM	NA

^*NA: not available