Filter Type |
PE Recurrence |
Complications |
Conclusion |
TrapEase Kalva et al., [62] Tsui et al., [63] |
7.5% n=751 |
Filter fracture: 3.0% Trapped thrombus: 25.2% |
TrapEase effective at preventing PE with minimal complications. |
1.5% n=582 |
Recurrent DVT in 18.7% of patients. Filter fracture in 13.3%. |
PE breakthrough rates were similar to other filters despite the double basket design. |
Denali Stavropoulus et al., [64] |
3% n=200 |
No incidences of filter fracture or migration |
Denali filter found to have high placement and retrieval success with few complications. |
Recovery (Bard) Kalva et al., [65] |
3% at mean follow-up of 63 days n=96 |
Penetration of IVC by filter arms in 11.5%, with fracture occurring in 3.1% of cases. No filter migration of caval occlusion. |
This version of the Recovery filter has structural weaknesses leading to a high incidence of IVC wall penetration and asymmetric deployment of filter legs. |
Sentry bio convertible Dake et al., [9] |
0 % at 1 year 2.4% at 2 years n=129 |
No filter related complications |
Sentry filters are effective at preventing PE, with a high rate of intended bioconversion and few complications |
OptEase Ziegler et al., [67] Kalva et al., [66] |
0% at 6 months n=150 |
Filter migration: 0.9% Symptomatic DVT: 0.8% |
OptEase filters provide protection from PE with a stable amount of complications between 1 and 6 month follow-ups. |
No PE on CT at 20 month follow-up n=71 |
Symptoms of PE developed in 15% of patients after filter insertion. No cases of filter migration, caval wall occlusion, or filter tilting. |
OptEase filters can be successfully used to prevent recurrence of PE with an acceptable complication rate. |
Gunther Tulip Given et al., [68] Looby et al. [69] |
0.3% PE n=317 |
3 filter placements resulted in minor transient abnormalities |
Gunther Tulip filters can provide significant protection against PE with limited complications if removed within the appropriate retrieval window. |
0.7% PE n=147 |
Pneumothorax occurred in 2.7% of patients and filter expansion occurred in 0.7% of patients. |
Gunther Tulip retrievable filters can be used safely and with minimal complications. |
Celect Sangwaiya et al., [70] |
2.8% at mean follow-up of 68 days n=73 |
Significant filter-tilt in 6.5% of placements Filter-related problems in 39% of cases. |
Celect filters can be placed safely and reduce incidence of PE, but show a high risk of caval filter leg penetration. |
Celect Platinum Lee, Brian et al., [71] |
2.6%-7.7% of PE (one confirmed and two additional on follow-up CT pulmonary angiogram) n=335 |
IVC perforation in 19.4% of cases. New in-filter thrombus in 8.7% (8.1% nonocclusive, 0.6% occlusive). Filter tilt in 1.2%. Filter migration in 0.3%. No instances of filter fracture. |
Complication rates of the Celect Platinum filter are in line with those of other models. |
VenaTech Lin et al., [11] |
0% at 6 months n=149 |
IVC perforation in 1.3% of converted No clinically significant filter migration, filter fracture, or IVC thrombosis in converted patients 14.3% IVC thrombosis in non-converted cases. |
At 6 month follow-up, the converted version of the VenaTech filter showed low risk of PE and minimal adverse effects. Non-converted configuration showed a higher rate of IVC thrombosis. |
Option Johnson et al., [72] |
8% within 180 days n=100 |
2% filter migration 3% symptomatic caval thrombosis |
Option IVC filters can be placed safely while maintaining a high rate of clinical success. |
Greenfield Kazmers et al., [73] |
Not used as endpoint n=151 |
1.3 % major complication rate 0.7% filter misplacement |
Greenfield filters can be placed safely with minimal risk of misplacement or complication. 30-day mortality rate of 6.6% with a mean survival time of 4.96 years following insertion. |
Greenfield vs. TrapEase Usoh et al., [74] |
Not a primary endpoint n=84 (Greenfield) n=72 (TrapEase) |
Thrombosis of either the iliac or IVC occurred in 7% of the TrapEase cohort. No incidence of filter migration, access-site thrombosis, or IVC perforation in either group. |
TrapEase filters showed a higher risk of thrombosis than the Greenfield IVC filters. |
Gunther Tulip (GT) vs. Trap/OptEase (TE/OE) vs. ALN vs. VenaTech (VT) Filters Koizumi et al., [76] |
Embolization into the pulmonary arteries occurred in one of the two cases of filter fracture in the GT group, and three out of 19 cases in the TE/OE group. ALN and VT groups had no incidences of fracture or PE. |
Filter fracture occurred in 0/19 in the ALN group, 0/2 in the VT group, 2/270 (0.7%) in the GT group, and 19/135 (14.1%) in the TE/OE group. |
TE/OE filters have a high frequency of complication and are not well suited for long-term or permanent insertion. |
Celect vs. Gunther Tulip vs. Greenfield McLoney et al. , [75] |
Not an endpoint n=255 (Celect) n=160 (GT) n=50 (Greenfield) |
Perforation was seen in 49%, 43%, and 2% in Celect, GT, and Greenfield filters, respectively. Filter fracture occurred in 0.8%, 0.6%, and 0% in the Celect, GT, and Greenfield groups. |
Greenfield filters had a significantly lower rate of perforation than Celect and GT filters. All three models had low incidences of fracture. |