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. Author manuscript; available in PMC: 2023 Jun 6.
Published in final edited form as: Neuroimage Rep. 2022 Jan 18;2(1):100082. doi: 10.1016/j.ynirp.2022.100082

Fig. 2.

Fig. 2.

Intracortical myelination reductions in children with ADHD + PAE and with ADHD-PAE compared to TD children. The ADHD + PAE and ADHD-PAE groups considered jointly (ADHD ± PAE) showed significantly (pfwe<0.05) reduced myelination in the deep (5–25% of the cortical thickness from the white-gray boundary), lower-middle (30–50% of the cortical thickness from the white-gray boundary), lower-upper cortical layers (55–75% of the cortical thickness from the white-gray boundary). When compared against TD children separately, the ADHD-PAE group showed more spatially extensive reduction in myelination than the ADHD + PAE group. ADHD, attention deficit hyperactivity disorder; PAE, prenatal alcohol exposure; TD, typically developing.