Table 4.
Associations between metabolomic principal component (PC) scores and lipid profile outcomes among 136 participants in Meta-Air study.
| Lipid profiles | PC1 | PC2 | PC3 | |||
|---|---|---|---|---|---|---|
| β | p-value | β | p-value | β | p-value | |
| Triglycerides a | 0.005 | 0.801 | 0.003 | 0.902 | −0.026 | 0.461 |
| Total cholesterol | −2.938 | 0.021* | 2.958 | 0.119 | 3.159 | 0.208 |
| HDL-cholesterol | −0.116 | 0.736 | 0.438 | 0.387 | 1.163 | 0.08 |
| LDL-cholesterol | −2.81 | 0.009* | 2.558 | 0.112 | 2.587 | 0.225 |
| VLDL-cholesterol a | 0.005 | 0.802 | 0.003 | 0.902 | −0.026 | 0.461 |
Associations reflects the change in lipid profiles measures (effect estimate β) per 1 unit change of principal component (PC) score. All associations are adjusted by covariates including age, sex, body fat percent, cigarette smoking, ethnicity/race, parental education, and community.
p < 0.05
log-transformed variables