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. Author manuscript; available in PMC: 2023 Jun 6.
Published in final edited form as: Sci Transl Med. 2023 Apr 19;15(692):eade9078. doi: 10.1126/scitranslmed.ade9078

Fig. 1. D57 LV-MN50 titers are more highly correlated with D57 spike IgG concentrations and with D57 RBD IgG concentrations than with D57 PsV-nAb ID50 titers or with D57 PsV-nAb ID80 titers.

Fig. 1.

Analyses were conducted in baseline SARS-CoV-2–negative per-protocol vaccine recipients in the immunogenicity sub-cohort. Corr indicates the baseline variable-adjusted Spearman rank correlation. ID50, 50% inhibitory dilution; ID80, 80% inhibitory dilution; LV, live virus; MN50, 50% microneutralization dilution; nAb, neutralizing antibody; PsV, pseudovirus. Correlations among spike IgG, RBD IgG, PsV-nAb, ID50, and PsV-nAb ID80 were reported previously [figure S6 of (10)]. Serological assay readouts are expressed in values relative to the World Health Organization (WHO) International Standard for anti–SARS-CoV-2 immunoglobulin (27). bAb readouts were converted to bAb units per milliliter (BAU/ml), and PsV-nAb titers and microneutralization assay readouts were calibrated to international units per milliliter (IU50/ml or IU80/ml).