Table 1. Optimization of Alkynylation of Quinolinium Triflates.
| entry | silyl triflate | base | yield (%) | ee (%) |
|---|---|---|---|---|
| 1 | TMSOTf | iPr2NEt | 30 | 9 |
| 2 | TBSOTf | iPr2NEt | 15 | 13 |
| 3 | TIPSOTf | iPr2NEt | 40 | 22 |
| 4 | TIPSOTf | NEt3 | 19 | 24 |
| 5 | TIPSOTf | Cy2NEt | 82 | 26 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.