Table 3.
Subjective Sleep Quality and Other Outcomes Between the Two Groups
| Factors | All Enrolled Patients | P value | Patients Included for Sleep Architecture Analyses | P value | ||
|---|---|---|---|---|---|---|
| Dexmedetomidine (N=20) | Control (N=20) | Dexmedetomidine (N=17) | Control (N=18) | |||
| Subjective sleep quality on the first postoperative morning | 73.5 ± 4.2 | 56.8 ± 4.2 | <0.0001a | 73.4 ± 4.6 | 57.0 ± 4.1 | <0.0001a |
| RASS | 2(2, 2) | 2(2, 2) | 0.738b | 2(2, 2) | 2(2, 2) | 0.968b |
| Pain score | 21.9 ± 2.8 | 23.4 ± 2.7 | 0.090a | 22.0 ± 2.9 | 23.4 ± 2.8 | 0.167a |
| At rest | ||||||
| 3 | 1(1, 2) | 2(2, 3) | <0.0001b | 1(1, 1) | 2(2, 3) | <0.0001b |
| 6 | 1(1, 1) | 2(2, 2) | <0.0001b | 1(1, 1) | 2(2, 2) | <0.0001b |
| 24 | 1(1, 1) | 2(2, 2) | <0.0001b | 1(1, 1) | 2(2, 2) | <0.0001b |
| At active | ||||||
| 3 | 2(2, 2) | 3(3, 3) | <0.0001b | 2(2, 2) | 3(3, 3) | <0.0001b |
| 6 | 2(2, 2) | 3(3, 3) | <0.0001b | 2(2, 2) | 3(3, 3) | <0.0001b |
| 24 | 2(1.3, 2) | 3(3, 3) | <0.0001b | 2(1, 2) | 3(3, 3) | <0.0001b |
| PCA consumption on the first 24h postoperatively (mL) | 36.8 ± 1.2 | 41.7 ± 1.0 | <0.0001a | 36.8 ± 1.3 | 41.7 ± 1.0 | <0.0001a |
| Desaturation | 0 | 0 | – | 0 | 0 | – |
| Occurrence of delirium | 0 | 0 | – | 0 | 0 | – |
Notes: Data are shown as mean (SD) or median (IQR) or number. aStudent’s t-test; bMann–Whitney U.
Abbreviations: RASS, Ramsay sedation scale; PCA, patient controlled analgesia; ICU, Intensive care unit; RASS, Richmond Agitation Sedation Scale; PSG, Polysomnography; NREM, Non-Rapid Eye Movement; REM, Rapid Eye Movement.