Table 2.
Baseline descriptive statistics of the CSWG study population by shock etiology
| Overall (N=1414) |
Shock Etiology | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| MI (N=494) | HF (N=712) | p-value | ||||||||
|
| ||||||||||
| n | (%) | n | (%) | n | (%) | |||||
| SCAI Stage | <0.001 | |||||||||
| B | 1 | (0.1) | 0 | (0) | 1 | (0.34) | ||||
| C | 232 | (16.4) | 75 | (26.0) | 139 | (47.9) | ||||
| D | 220 | (15.6) | 114 | (39.6) | 85 | (29.3) | ||||
| E | 192 | (13.6) | 99 | (34.4) | 65 | (22.4) | ||||
| # Pressors/Inotropes | <0.001 | |||||||||
| 0 | 236 | (16.7) | 86 | (18.8) | 119 | (17.6) | ||||
| 1 | 393 | (27.8) | 115 | (25.2) | 241 | (35.7) | ||||
| 2+ | 650 | (46.0) | 256 | (56.0) | 316 | (46.8) | ||||
| # MCS Devices | <0.001 | |||||||||
| 0 | 224 | (15.8) | 21 | (4.3) | 161 | (22.6) | ||||
| 1 | 882 | (62.4) | 294 | (59.5) | 465 | (65.3) | ||||
| 2+ | 308 | (21.8) | 179 | (36.2) | 86 | (12.1) | ||||
| Type of MCS | ||||||||||
| Impella | 410 | (29.0) | 210 | (42.5) | 148 | (20.8) | <0.001 | |||
| ECMO | 333 | (23.6) | 169 | (43.2) | 106 | (14.9) | <0.001 | |||
| IABP | 770 | (54.5) | 292 | (59.1) | 382 | (53.7) | 0.06 | |||
| Gender | 0.005 | |||||||||
| Female | 387 | (27.4) | 153 | (31.0) | 169 | (23.7) | ||||
| Male | 1025 | (72.5) | 340 | (68.8) | 543 | (76.3) | ||||
| Race | <0.001 | |||||||||
| White | 647 | (45.8) | 175 | (35.4) | 321 | (45.1) | ||||
| Hispanic/Latino | 31 | (2.2) | 16 | (3.2) | 7 | (1.0) | ||||
| Asian | 31 | (2.2) | 18 | (3.6) | 4 | (0.6) | ||||
| African-American | 28 | (2.0) | 8 | (1.6) | 13 | (1.8) | ||||
| Other | 82 | (5.8) | 15 | (3.0) | 55 | (7.7) | ||||
| Medical History | ||||||||||
| HTN | 681 | (48.2) | 321 | (65.0) | 276 | (38.8) | <0.001 | |||
| DM | 489 | (34.6) | 220 | (44.5) | 222 | (31.2) | <0.001 | |||
| Afib/Flutter | 296 | (20.9) | 37 | (7.5) | 227 | (31.9) | <0.001 | |||
| CKD (any stage) | 323 | (22.8) | 84 | (17.0) | 207 | (29.1) | <0.001 | |||
| PVD | 60 | (4.2) | 27 | (5.5) | 22 | (3.1) | 0.0177 | |||
| COPD | 101 | (7.1) | 27 | (5.5) | 62 | (8.7) | 0.0028 | |||
| CVA/TIA | 159 | (11.2) | 60 | (12.1) | 88 | (12.4) | 0.2023 | |||
| Valvular Disease | 214 | (15.1) | 24 | (4.9) | 154 | (21.6) | <0.001 | |||
| PCI | 293 | (20.7) | 160 | (32.4) | 101 | (14.2) | <0.001 | |||
| CABG | 114 | (8.1) | 40 | (8.1) | 60 | (8.4) | 0.0135 | |||
| VT | 216 | (15.3) | 37 | (7.5) | 154 | (21.6) | <0.001 | |||
| ICD | 329 | (23.3) | 15 | (3.0) | 287 | (40.3) | <0.001 | |||
| CRT | 97 | (6.9) | 10 | (2.0) | 86 | (12.1) | <0.001 | |||
| n | Mean | (SD) | n | Mean | (SD) | n | Mean | (SD) | ||
|
| ||||||||||
| Demographic | ||||||||||
| Age | 1412 | 59.9 | (14.8) | 493 | 64.9 | (12.8) | 712 | 57.9 | (14.1) | <0.001 |
| Weight (kg) | 1138 | 85.3 | (22.6) | 403 | 83.2 | (19.5) | 534 | 86.5 | (24.6) | 0.027 |
| Metabolic | ||||||||||
| AST | 788 | 459.4 | (1492.6) | 345 | 448.5 | (1066.3) | 328 | 441.4 | (1805.2) | 0.950 |
| BUN | 1026 | 32.4 | (20.5) | 416 | 28.3 | (17.8) | 456 | 37.7 | (22.6) | <0.001 |
| Lactate | 676 | 4.4 | (4.2) | 292 | 4.7 | (4.1) | 307 | 3.8 | (4.1) | 0.011 |
| HCO3 | 836 | 22.1 | (5.4) | 367 | 20.2 | (4.9) | 330 | 24.3 | (5.3) | <0.001 |
| Serum Creatinine | 1295 | 1.8 | (1.1) | 448 | 1.7 | (1.2) | 687 | 1.9 | (1.1) | 0.003 |
| pH | 577 | 7.3 | (0.2) | 306 | 7.3 | (0.2) | 179 | 7.3 | (0.1) | <0.001 |
| Hemodynamic | ||||||||||
| Admission EF | 771 | 24.9 | (15.5) | 260 | 30.9 | (15.9) | 429 | 20.2 | (12.4) | <0.001 |
| RAP | 1037 | 14.2 | (6.9) | 303 | 14.6 | (6.5) | 626 | 14.0 | (7.2) | 0.176 |
| PCWP | 847 | 24.5 | (8.9) | 271 | 24.2 | (9.2) | 486 | 24.8 | (8.8) | 0.354 |
| Mean PAP | 904 | 32.8 | (9.8) | 257 | 30.2 | (9.0) | 549 | 34.4 | (9.8) | <0.001 |
| Cardiac Output | 1062 | 3.8 | (2.4) | 329 | 3.8 | (2.1) | 630 | 3.8 | (2.4) | 0.826 |
| CPO | 999 | 0.6 | (0.4) | 314 | 0.6 | (0.4) | 584 | 0.6 | (0.4) | 0.638 |
| Heart Rate | 1248 | 92.0 | (22.7) | 407 | 91.2 | (23.0) | 660 | 92.2 | (22.1) | 0.474 |
| Cardiac Index | 1071 | 1.9 | (0.6) | 335 | 1.9 | (0.6) | 635 | 1.8 | (0.6) | 0.096 |
| MAP | 1230 | 74.5 | (14.7) | 433 | 74.9 | (16.9) | 628 | 74.0 | (12.7) | 0.483 |
p-values calculated using chi-sq test of independence or t-test as appropriate. Abbreviations: Afib: Atrial fibrillation; AST: aspartate aminotransferase; BUN: blood urea nitrogen; CABG: coronary artery bypass grafting; CKD: chronic kidney disease; COPD: chronic obstructive pulmonary disease; CPO: cardiac power output; CRT: cathode-ray tube; CVA: cerebrovascular accident; HCO3: Bicarbonate; HTN: Hypertension; ICD: implantable cardioverter defibrillator; MAP: mean arterial pressure; PAP: pulmonary arterial pressure; PCI: percutaneous coronary intervention; PCWP: pulmonary capillary wedge pressure; PVD: peripheral vascular disease; RAP: right arterial pressure; TIA: transient ischemic attack; VT: ventricular tachycardia