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. Author manuscript; available in PMC: 2023 Sep 9.
Published in final edited form as: J Med Chem. 2023 Feb 24;66(5):3372–3392. doi: 10.1021/acs.jmedchem.2c01858

Scheme 3. Generic Synthesis of Class I (34a–h) and III (35a–g) Compoundsa.

Scheme 3.

aReagents and conditions: (a) compound 32 or 33, NaH, THF, 0 °C to RT; (b) Pd(PPh3)3, Na2CO3, phenylboronic acid, EtOH/H2O, reflux.