Table 1.
Clinical Characteristics of ZFTA-RELA Fused ST-EPN Patients
| Characteristic | Patients (N = 108) |
|---|---|
| Sex | |
| Male – no. (%) | 65 (60.2%) |
| Female – no. (%) | 43 (39.8%) |
| Age | |
| Median, y | 6 y 7 months |
| Range, y | 5 months–18 y 7 months |
| WHO grading | |
| Grade II | 14 (13%) |
| Grade III | 73 (67.6%) |
| unknown | 21 (19.4%) |
| Extent of surgical resection | |
| Gross total resection (GTR) | 84 (77.8%) |
| Subtotal resection (STR) | 24 (22.2%) |
| Radiotherapy | |
| Yes | 98 (90.7%) |
| No | 10 (9.3%) |
| Chemotherapy | |
| Yes | 63 (58.3%) |
| E-HIT Stratum A | 29 (26.9%) |
| E-HIT Stratum B | 16 (14.8%) |
| E-HIT Stratum C | 4 (3.7%) |
| ACNS 0831 | 5 (4.6%) |
| ICE | 3 (2.8%) |
| Personalized treatment | 2 (1.9%) |
| HIT 91 | 1 (0.9%) |
| CCLG 2007 | 1 (0.9%) |
| SIOP ependymoma II | 1 (0.9%) |
| No | 45 (41.7%) |
| Relapse/recurrence disease | |
| Local | 21 (19.4%) |
| Distant | 3 (2.8%) |
| Combined local/distant | 1 (0.9%) |
| Unknown | 14 (13%) |