Table 3.

Efficacy of Surgical Resection or Radiosurgery for Meningioma in Seizure Control

Efficacy of surgery and radiotherapy in seizure control
Study	Factors that influence surgical seizure control
Gadot et al. 17	Seizure freedom was attained in 74% of patients following meningioma resection with a median follow up period of 17 months. Resolution of seizure postoperatively was associated with lack of postresection ischemia, lack of recurrent disease, lower WHO grade and lower MIB-1 index
Chaichana et al. 18	In this cohort, 90% of patients remained seizure-free in a 48-month period following primary resection of WHO grade 1 meningioma
Schneider et al. 19	In 187 patients with meningioma who had seizures preoperatively, 169 (90%) achieved seizure freedom following surgical resection of meningioma. Predictors for continuation of seizures postoperatively included low extent of resection, larger PTE diameter and greater WHO grade
Xue et al. 9	In 21 patients with meningioma who had seizures preoperatively, 8 (38.1%) achieved seizure freedom following surgical resection of the meningioma
El-Khatib et al. 20	129 patients were followed for a median of 12 years following stereotactic linear accelerator radiosurgery for meningioma. In this cohort, 77 patients (59.7%) displayed neurological improvement or decreased seizure burden
Englot et al. 20162	69.3% of 703 patients diagnosed with preoperative seizures became seizure-free post-resection of meningioma. Seizure postoperatively was twice as likely in patients with PTE
Hwang et al. 201921	The most significant predictors of seizure following radiosurgery were peritumoral edema (odds ratio, 53.99; 95% confidence interval, 5.214–559.1; P = .001) and brain tumor contact-surface index (odds ratio, 2.466; 95% confidence interval, 1.183–5.138; P = .016)
El-Khatib et al. 201122	Of 129 participants, the neurological symptoms existing before SRS improved in 77 patients (59.7 %), remained unchanged in 42 (32.6 %), and deteriorated in 10 (7.8 %) patients