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. 2023 Mar 3;212(3):262–275. doi: 10.1093/cei/uxad034

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© The Author(s) 2023. Published by Oxford University Press on behalf of the British Society for Immunology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — BAL T-cell sub-populations differentially express MALAT1-correlated genes. (A) Bar plots showing the number of genes that correlate or anti-correlate with MALAT1 for all T cells, CD4+ and CD8+ T cells. (B) Venn diagrams depicting the intersection of gene lists that correlated [Corr(CD8), Corr(CD4)] and that for those that anti-correlated [Acorr(CD8), Acorr(CD4)] with MALAT1 expression in CD4+ cells and CD8+ cells. (C) Heatmap of top 25 MALAT1 correlating genes (highlighted in the rectangle) and top 25 anti-correlating genes in CD4 + T cells grouped by their cluster identities and by sub-population. Heatmap legend indicates expression values scaled to a mean of zero. (D) Same as C but for CD8+ T cells.