Table 3.

Associations between demographic characteristics and the glutamatergic level in the ACC in the three groups

		Non-TRS (n = 35)		TRS (n = 38)		Control (n = 19)
		Statistics	p	Statistics	p	Statistics	p
Sex	Glx/NAAx	0.75	0.46	1.50	0.14	0.14	0.89
	Glu/NAAx	0.23	0.82	1.77	0.08	0.39	0.70
Age	Glx/NAAx	−0.13	0.46	−0.24	0.15	0.37	0.12
	Glu/NAAx	−0.35	0.04*	−0.11	0.52	0.23	0.33
Educational level	Glx/NAAx	−0.36	0.84	−0.27	0.11	−0.09	0.73
	Glu/NAAx	0.15	0.41	−0.23	0.17	−0.18	0.06
WMI	Glx/NAAx	−0.42	0.01*	−0.2	0.23	0.07	0.78
	Glu/NAAx	−0.23	0.19	−0.15	0.38	0.36	0.14
PANSS	Glx/NAAx	−0.26	0.14	0.12	0.48	NA
	Glu/NAAx	−0.16	0.54	0.09	0.61	NA

TRS, treatment-resistant schizophrenia; ACC, anterior cingulate cortex; Glu, glutamate; Glx, total glutamate + glutamine; NAAx, N-acetylaspartate + N-acetyl aspartylglutamate; WMI, working memory index; PANSS, positive and negative syndrome scale.

Note: The statistics shown are from the t test for sex, while Pearson's R was used for the other demographic characteristics.

*p < 0.05.