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. Author manuscript; available in PMC: 2023 Jun 7.
Published in final edited form as: Acta Neuropathol. 2022 Dec 5;145(1):1–12. doi: 10.1007/s00401-022-02521-5

Fig. 4. TSC1 and TSC2 variants show differing tau phosphorylation and acetylation in TSC.

Fig. 4

Immunoblots performed on frozen tissue homogenates from inferior frontal gyrus tissue of control, non-TSC epilepsy (EP 6, EP 9), and TSC subjects with TSC1 (TS 6) or TSC2 mutations (TS 7, TS 10). Antibodies used include CP13, PHF1, and MAB359 and were normalized to total protein stain. Ac-tau and, to a lesser extent, p-tau, was more abundant in subjects with TSC tauopathy compared with other groups.