Table 1.
Subject clinical and demographic characteristics
| Case# | Age (years) | Sex (M:F) | PMI (hours) |
Clinical diagnosis | NIH Biobank (source) | |
|---|---|---|---|---|---|---|
| TSC | TS 1 (TSC2) | 30 | M | 3.0 | Tuberous Sclerosis | Maryland |
| TS 2 (TSC2) | 34 | F | 5.0 | Tuberous Sclerosis | Maryland | |
| TS 3 (N/A) | 39 | F | 16.0 | Tuberous Sclerosis | Maryland | |
| TS 4 (TSC2) | 40 | F | 18.0 | Tuberous Sclerosis | Maryland | |
| TS 5 (TSC2) | 42 | F | 15.0 | Tuberous Sclerosis | Maryland | |
| TS 6 (TSC1) | 46 | M | 1.0 | Tuberous Sclerosis | Maryland | |
| TS 7 (TSC2) | 47 | F | 3.0 | Tuberous Sclerosis | Maryland | |
| TS 8 (TSC2) | 55 | M | 23.0 | Tuberous Sclerosis | Maryland | |
| TS 9 (TSC2) | 56 | F | 14.0 | Tuberous Sclerosis | Maryland | |
| TS 10 (TSC2) | 58 | M | 17.0 | Tuberous Sclerosis | Maryland | |
| TS 11 (TSC2) | 58 | F | 20.0 | Tuberous Sclerosis | Maryland | |
| 45.9 (SD) | 4:7 | 12.2 (SD) | ||||
| Epilepsy (non-TSC) | EP 1 | 26 | F | 19.0 | Epilepsy | Maryland |
| EP 2 | 32 | F | 28.0 | Epilepsy | Maryland | |
| EP 3 | 39 | M | 15.0 | Epilepsy; Intellectual Disability NOS | Maryland | |
| EP 4 | 42 | F | 29.0 | Epilepsy | Maryland | |
| EP 5 | 42 | F | 21.0 | Epilepsy | Maryland | |
| EP 6 | 43 | M | 22.0 | Epilepsy | Maryland | |
| EP 7 | 46 | M | 14.0 | Epilepsy; Cerebrovascular Accident | Maryland | |
| EP 8 | 51 | F | 32.3 | Epilepsy | Harvard | |
| EP 9 | 55 | F | 18.0 | Epilepsy; ASD | Maryland | |
| 41.8 (SD) | 3:6 | 22.0 (SD) | ||||
| Control | Control 1 | 24 | F | 17.9 | Alcohol abuse, BPD 1, cocaine abuse | Miami |
| Control 2 | 34 | M | 26.7 | Control | Mt. Sinai | |
| Control 3 | 41 | F | 10.7 | Control | Mt. Sinai | |
| Control 4 | 42 | M | 6.0 | Control | Mt. Sinai | |
| Control 5 | 43 | F | 21.5 | MDD | Miami | |
| Control 6 | 45 | F | 24.5 | BPD | Mt. Sinai | |
| Control 7 | 46 | M | 14.8 | Control | Mt. Sinai | |
| Control 8 | 49 | M | 12.8 | Control | Mt. Sinai | |
| Control 9 | 56 | M | 18.8 | MDD | Mt. Sinai | |
| Control 10 | 58 | M | 16.8 | Control | Mt. Sinai | |
| 43.8 (SD) | 6:4 | 17.0 (SD) |
ASD, autism spectrum disorder; BPD, borderline personality disorder; MDD, major depressive disorder; NOS, not otherwise specified; TSC, Tuberous Sclerosis Complex; F, female; M, male; PMI, postmortem interval from death to autopsy; SD, standard deviation.