Table 2.
Relationship between exosomal IGLV1-40 or IGHV4-4 expression and clinicopathological parameters in NSCLC
| Characteristics | No. cases | IGLV1-40 | IGHV4-4 | ||
|---|---|---|---|---|---|
|
|
|
||||
| Median (ng/mL) | P-value | Median (ng/mL) | P-value | ||
| Age (year) | |||||
| <60 | 18 | 1.537 | 0.271 | 1.211 | 0.158 |
| ≥60 | 53 | 1.281 | 1.534 | ||
| Sex | |||||
| Male | 51 | 1.355 | 0.989 | 1.531 | 0.204 |
| Female | 20 | 1.358 | 1.251 | ||
| Smoking status | |||||
| Smoker | 38 | 1.366 | 0.913 | 1.372 | 0.415 |
| Non-smoker | 33 | 1.344 | 1.344 | ||
| Histological type | |||||
| Adenocarcinoma | 57 | 1.374 | 0.577 | 1.336 | 0.407 |
| Squamous cell | 14 | 1.231 | 1.212 | ||
| Metastasis | |||||
| Positive | 45 | 1.073 | 0.002** | 1.239 | 0.004** |
| Negative | 26 | 1.817 | 1.822 | ||
**
represents a comparison between metastatic cancer and lung metastatic cancer, P<0.01.