Table 1.
Multivariate cox regression analysis of IMvigor210 cohort
| Variable | Group | N | B | SE | Wald | P | HR | 95% CI |
|---|---|---|---|---|---|---|---|---|
| Sex | ||||||||
| female* | 59 | |||||||
| male | 221 | -0.198 | 0.175 | 1.279 | 0.258 | 0.82 | 0.582-1.157 | |
| Race | ||||||||
| white* | 257 | |||||||
| black | 15 | -0.396 | 0.388 | 1.043 | 0.307 | 0.673 | 0.315-1.439 | |
| other | 8 | -0.718 | 0.508 | 1.996 | 0.158 | 0.488 | 0.18-1.321 | |
| Immune phenotype | ||||||||
| excluded* | 132 | |||||||
| desert | 75 | -0.007 | 0.18 | 0.001 | 0.969 | 0.993 | 0.698-1.413 | |
| inflamed | 73 | -0.282 | 0.203 | 1.922 | 0.166 | 0.755 | 0.507-1.124 | |
| TCGA Subtype | ||||||||
| I-II* | 110 | |||||||
| III-IV | 170 | -0.223 | 0.155 | 2.077 | 0.149 | 0.8 | 0.591-1.083 | |
| PDCD1 | ||||||||
| HIGH* | 111 | |||||||
| LOW | 169 | -0.224 | 0.199 | 1.267 | 0.26 | 0.8 | 0.542-1.18 | |
| CXCL10+CCL5 | ||||||||
| HIGH* | 104 | |||||||
| LOW | 176 | 0.454 | 0.209 | 4.717 | 0.03 | 1.575 | 1.045-2.373 |
*
Control group.