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. 2023 Jun 5;26(6):1032–1041. doi: 10.1038/s41593-023-01316-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 7 — a, Timeline of ocular dominance plasticity experiment. b, LSD treatment combined with monocular deprivation induces an ocular dominance shift in the primary visual cortex of mice in favor of the opened eye. c, d, Time course of the head-twitch response immediately after LSD administration for data shown in Fig. 7c, d. e-n, Locomotor activity at baseline (e), fear acquisition response (f) and single traces of fear conditioning and extinction data shown in Fig. 7i, j after the administration of saline or LSD to WT and Y433F^+/- mice and their effects in the short-term (g-j) and long-term (k-n). o-s, Locomotor activity at baseline (o) and single traces (p-s) of fear conditioning data shown in Fig. 7k on administration of saline or LSD in combination with or without extinction training. Data shown as mean ± s.e.m, *P < 0.05. Detailed statistics reported in Supplementary Table 1.