Table 4.
Summarized results of the interaction effect analysis
Interaction effects | BP | DVT | LAD | PE | IS | TP |
---|---|---|---|---|---|---|
T2DM×(mRNA-1273) (reference: T2DM× JNJ-78436735) | 1.26 (0.40–3.97) | 0.80 (0.22–2.91) | 1.44 (0.46–5.42) | 0.58 (0.20–1.65) | 1.68 (0.32–10.16) | 0.15 (0.02–0.80)a |
T2DM×(BNT162b2) (reference: T2DM× JNJ-78436735) | 2.17 (0.67–7.08) | 4.69 (1.26–18.77)a | 1.67 (0.54–6.24) | 2.78 (0.90–8.86) | 2.54 (0.45–16.84) | 0.21 (0.02–1.34) |
T2DM×(mRNA-1273) (reference: T2DM× BNT162b2) | 0.58 (0.31–1.07) | 0.17 (0.06–0.46)b | 0.87 (0.60–1.25) | 0.21 (0.08–0.48)b | 0.66 (0.19–2.18) | 0.72 (0.17–3.08) |
The odds ratio was calculated by multiple logistic regression analysis for each severe adverse event after adjusting for sex (reference: female), age, onset days, and vaccine type (reference: JNJ-78436735) as covariates. In the case of cerebral venous sinus thrombosis and encephalitis myelitis encephalomyelitis, the frequency of occurrence was very small (10 or less, respectively); therefore, the results are not presented in the table.
BP, Bell’s palsy; DVT, deep vein thrombosis; LAD, lymphadenopathy; PE, pulmonary embolism; IS, ischemic stroke; TP, thrombocytopenia; T2DM, type 2 diabetes mellitus.
P<0.05,
P<0.001.