Table 2.

The associations of mapped genes with colorectal cancer risk from gene-based analysis

Gene	Chr	Start	Stop	Z value	P-valuea
PIP4K2A	10	22 823 766	23 003 503	4.374	6.10 × 10−6
HLA-DPB1	6	33 043 703	33 057 473	4.318	7.86 × 10−6
RTEL1	20	62 289 163	62 327 606	3.582	1.70 × 10−4

^aThe statistically significant threshold is a P-value < 0.017 (0.05/number of genes tested).