Table 3.
Results of the phenome-wide association study for cervical cancer genetic risk score. Bonferroni correction was applied to select statistically significant associations (number of tested ICD main codes—2001, corrected P-value threshold 0.05/2001 = 2.5
10-5
| Diagnosis | P-value | ||||
|---|---|---|---|---|---|
| Overall | Female-only | Male-only | HLA fraction | non-HLA-fraction | |
| C53 Malignant neoplasm of cervix uteri | 2.1 10−14
|
2.1 10−14
|
NA | 1.1 10−11
|
2.1 10−4
|
| D06 Carcinoma in situ of cervix uteri | 8.9 10−7
|
3.2 10−7
|
NA | 1.1 10−3
|
1.2 10−4
|
| N87 Dysplasia of cervix uteri | 2.6 10−37
|
2.6 10−37
|
NA | 3.6 10−29
|
2.4 10−10
|
| B07 Viral Warts | 1.9 10−7
|
5.9 10−3
|
1.5 10−7
|
5.7 10−14
|
0.17 |
| B36 Other superficial mycoses | 1.7 10−7
|
2.5 10−7
|
0.09 | 1.3 10−11
|
0.76 |
| B97 Viral agents as the cause of diseases classified elsewhere | 2.0 10−12
|
1.4 10−13
|
0.42 | 4.0 10−11
|
3.5 10−3
|
| E06 Thyroiditis | 4.8 10−8
|
5.5 10−7
|
0.02 | 3.7 10−7
|
0.02 |
| L40 Psoriasis | 1.1 10−5
|
1.6 10−4
|
0.02 | 8.5 10−11
|
0.18 |
| L43 Lichen planus | 6.4 10−8
|
4.9 10−5
|
2.5 10−4
|
2.9 10−9
|
0.27 |
































