Table 3.
Results of the phenome-wide association study for cervical cancer genetic risk score. Bonferroni correction was applied to select statistically significant associations (number of tested ICD main codes—2001, corrected P-value threshold 0.05/2001 = 2.5 10-5
Diagnosis | P-value | ||||
---|---|---|---|---|---|
Overall | Female-only | Male-only | HLA fraction | non-HLA-fraction | |
C53 Malignant neoplasm of cervix uteri | 2.1 ![]() |
2.1 ![]() |
NA | 1.1 ![]() |
2.1 ![]() |
D06 Carcinoma in situ of cervix uteri | 8.9 ![]() |
3.2 ![]() |
NA | 1.1 ![]() |
1.2 ![]() |
N87 Dysplasia of cervix uteri | 2.6 ![]() |
2.6 ![]() |
NA | 3.6 ![]() |
2.4 ![]() |
B07 Viral Warts | 1.9 ![]() |
5.9 ![]() |
1.5 ![]() |
5.7 ![]() |
0.17 |
B36 Other superficial mycoses | 1.7 ![]() |
2.5 ![]() |
0.09 | 1.3 ![]() |
0.76 |
B97 Viral agents as the cause of diseases classified elsewhere | 2.0 ![]() |
1.4 ![]() |
0.42 | 4.0 ![]() |
3.5 ![]() |
E06 Thyroiditis | 4.8 ![]() |
5.5 ![]() |
0.02 | 3.7 ![]() |
0.02 |
L40 Psoriasis | 1.1 ![]() |
1.6 ![]() |
0.02 | 8.5 ![]() |
0.18 |
L43 Lichen planus | 6.4![]() |
4.9![]() |
2.5![]() |
2.9 ![]() |
0.27 |