Table 2.
Results comparing usual care with routine structured diet and PA intervention categories
| Incremental change due to intervention-by-intervention subgroup | |||||
|---|---|---|---|---|---|
| Outcome | Usual care | Base case (diet and/or PA) | Diet only | PA only | Diet and PA |
| Excluding NICU/SCN | |||||
| Health outcomes | |||||
| Cases of GDM | 37,957 | −12,526 (−17,341, −6923) | −19,905 (−21,508, −1350) | −14,424 (−21,585, −5171) | −9489 (−18,035, 1514) |
| Cases of type 2 diabetes | 85,219 | −8248 (−11,419, −4554) | −8498 (−14,158, −900) | −9498 (−14,199, −3419) | −6249 (−11,863, 1001) |
| YLLa | 5,773,306 | 2576 | 2654 | 2966 | 1951 |
| YLL with type 2 diabetesa | 328,625 | −45,739 | −47,125 | −52,669 | −34,651 |
| QALYsa | 5,123,076 | 10,748 | 11,074 | 12,376 | 8142 |
| Incremental QALYs per woman | 0.035 (0.020, 0.050) | 0.036 (0.004, 0.061) | 0.041 (0.015, 0.061) | 0.027 (−0.004, 0.051) | |
| Costs (AU$) | |||||
| Intervention cost | 0 | 69,904,575 | 54,142,597 | 60,265,867 | 69,934,187 |
| Pregnancy costs | 3,142,840,956 | −25,187,141 | −25,950,388 | −29,003,375 | −19,081,168 |
| Type 2 diabetes management | 425,992,395 | −60,108,916 | −61,930,398 | −69,216,327 | −45,537,057 |
| Total healthcare costsa | 3,568,833,351 | −15,391,482 | −33,738,190 | −37,953,836 | 5,315,962 |
| Incremental cost per woman | −50 (−230, 110) | −110 (−373, 153) | −124 (−373, 102) | 17 (−229, 267) | |
| ICER | Dominant | Dominant | Dominant | 653 | |
| PSA iterations within cost-saving quadrant (%) | 70.5 | 81.6 | 85.7 | 47.9 | |
| ROI ratio | 1.22 (0.53, 2.13) | 1.62 (0.16, 3.22) | 1.63 (0.50, 3.00) | 0.92 (−0.14, 2.05) | |
| Including NICU/SCN | |||||
| Health outcomes | |||||
| NICU/SCN admissions | 71,847 | −1704 (−2359, −941) | −1755 (−2925, −184) | −1962 (−2936, −703) | −1291 (−2453, 206) |
| Costs (AU$) | |||||
| NICU/SCN costs | 1,218,144,257 | −24,264,341 | −24,999,624 | −27,940,757 | −18,382,077 |
| Total healthcare costsa | 4,786,977,608 | −39,655,823 | −58,737,814 | −65,894,592 | −13,066,114 |
| Incremental cost per woman | −130 (−337, 57) | −192 (−629, 132) | −216 (−496, 63) | −43 (−341, 276) | |
| ICER | Dominant | Dominant | Dominant | Dominant | |
| PSA iterations within cost-saving quadrant (%) | 90.7 | 90.3 | 94.2 | 66.1 | |
| ROI ratio | 1.57 (0.75, 2.58) | 2.08 (0.20, 4.02) | 2.09 (0.69, 3.64) | 1.19 (−0.17, 2.55) | |
Values are means, with 95% CI in parentheses where applicable
aDiscounted at 5% discounting rate
PSA, probabilistic sensitivity analysis; YLL, years of life lived