Table 4.

Adverse events of the patient subgroup

	Control group					Experimental group
	Grade 2	Grade 3	Grade 4	Grade 5	Grade 2		Grade 3
Laboratory abnormalities
Anemia	1	1	None	none	None		None
Increased ALT/AST	2	None	None	none	None		None
Clinical adverse events
Abdominal pain	1	None	None	None	None		None
Cardiac arrest	None	None	None	1	None		None
Cerebral infarction	None	None	1	None	None		None
Constipation	2	None	None	None	None		None
Diarrhea	1	None	None	None	3		None
Dyspepsia	1	None	None	None	None		None
Fatigue	5	None	None	None	None		None
Headache	None	None	None	None	1		None
Hypertension	1	1	None	None	2		None
Lethargy	1	None	None	None	None		None

ALT Alanine aminotransferase; AST Aspartate aminotransferase