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. 2023 Jun 7;14(6):350. doi: 10.1038/s41419-023-05877-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A Sphere formation of PANC-1 cells and Mia PaCa-2 cells after the knockdown of UFL1. B Sphere formation of PANC-1 cells and Mia PaCa-2 cells after the overexpression of UFSP2. C The populations of ALDH1⁺ cells and CD44⁺-CD24⁺ cells in PANC-1 and Mia PaCa-2 cells after the knockdown of UFL1. The populations were analyzed by flow cytometry (n = 3). D The populations of ALDH1⁺ cells and CD44⁺-CD24⁺ cells in PANC-1 and Mia PaCa-2 cells after overexpressing UFSP2. The populations were analyzed by flow cytometry (n = 3). All experiments were independently repeated for 3 times, and the data are expressed as mean ± SD. ^*P < 0.05 indicates statistically significant versus negative control. ^**P < 0.01 indicates statistically very significant versus negative control.