Table 1.
Ten human cancers with the highest frequency of genetic alterations of BCL2L14 based on 310 cancer studies available on cBioPortal (www.cbioportal.org/).
| Alteration frequency | |||||
|---|---|---|---|---|---|
| Cancer type | Number of cases | Amplification | Deep deletion | Mutation | Structural variant |
| Ovarian cancer | 1106 | 7.23% | 0.54% | – | – |
| Germ cell tumor | 388 | 7.47% | – | – | – |
| B-lymphoblastic leukemia/lymphoma | 1026 | 0.39% | 7.02% | – | – |
| Hodgkin lymphoma | 28 | 7.14% | – | – | – |
| Lung cancer | 39 | 2.56% | 2.56% | – | – |
| Invasive breast carcinoma | 950 | 2.84% | 0.74% | 0.21% | – |
| T-lymphoblastic leukemia/lymphoma | 92 | – | 3.26% | – | – |
| Breast cancer | 5328 | 1.93% | 0.88% | 0.02% | 0.08% |
| Skin cancer, non-melanoma | 364 | – | – | 2.75% | – |
| Pancreatic cancer | 2508 | 1.79% | 0.16% | 0.16% | – |
Only studies reporting combined data on structural variants, mutation and copy number alterations were selected for table preparation.