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. 2023 Apr 20;30(6):1550–1562. doi: 10.1038/s41418-023-01164-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Exogenous interaction between TRAF2 and p62 in HepG2 and HuH7 cells. WCE: whole-cell extracts. B Endogenous interaction of TRAF2 and p62. *: IgG heavy chain. C A schematic representation of TRAF2 deletion mutants(up), and the interaction between p62 and TRAF2 truncations (below). D Mapping of p62 regions interaction with TRAF2 (up), and the interaction of TRAF2 with p62 mutants (below). *: non-specific band. E The binding model of TRAF2 with p62.