Skip to main content
. 2023 May 24;10:1144677. doi: 10.3389/fnut.2023.1144677

Table 2.

Nanoencapsulation of polyphenolic compounds polysaccharide and protein-based nanostructures.

Encapsulating material Phenolic compound Method Size (nm) Zeta potential (mV) Encapsulation efficiency (%) Purpose Reference
Pectin - Cellulose A blend of phenolic compounds extracted from pomegranate peel Nanoemulsion ~200 ~20 Highest antimicrobial activity (220)
Carboxymethyl chitosan Epigallocatechin gallate Ionic cross-linking 400 +36.6 75 Increase antitumor activity (222)
Pectin – WPC Olive leaf phenolic compounds Nanoemulsion 347.7 72.73 to 96.64 Increased antioxidant properties and release rate (205)
Pectin – WPI Anthocyanin Self-assembly 200 −36 55 Improve Stability (184)
Carboxymethyl chitosan Anthocyanin Ionic interaction 219.53 63.15 Promote stability and inhibit degradation in the gastrointestinal tract (224)
Chitosan Catechins Polyanion-gelation 169.0 to 201.4 ~ +30 24 to 53 Targeted delivery system (225)
Chitosan and β-lactoglobulin Epigallocatechin gallate Ionic gelation 100 to 500 +10 to +35 ~ 60 To release epigallocatechin gallate in the gastrointestinal tract (226)
Chitosan-Alginate Anthocyanins Ionic pre-gelation and polyelectrolyte complex formation 358.5 to 635.9 56.87 to 68.9 Maintenance of antioxidant activity (227)
Chitosan Anthocyanin Ionic gelation 160 to 1,093 To stabilize the color and the antioxidant activity (228)
Chitosan - β-Lactoglobulin Anthocyanin Ionic gelation 91,71 69.33 To improve stability and bioavailability (223)
Soybean insoluble dietary fiber Anthocyanin (Malvidin-3-O-glucoside) Emulsification 300 Storage stability and protection of color (229)
Chitosan Anthocyanin Ionotropic gelation 274 to 455 −5.04 to −35.4 70 To improve in vivo antioxidant potential (230)
Pectin Resveratrol Antisolvent precipitation and electrostatic deposition 120 −30 Stability, Bioaccessibility, and Antioxidant Capacity Maintenance (218)
Pectin–Chitosan Anthocyanins Self-assembly 100–300 66.68 Molecular Stability and Control Released (215)
Pectin–Lysozyme Anthocyanins Self-assembly 198.5 −26 73 Molecular Stability (18)
Chitosan–Pectin Anthocyanin Polyelectrolyte complex + 37 to +55.5 60 Color protection and application in food packaging (221)
Pectin-Chitosan Anthocyanin Nanoliposomes 64 to 352 −30 to +21 28.54 to 61.17 To investigate the protective effect of hepatocytes injury in L02 cells (231)
Hohenbuehelia serotina polysaccharides Quercetin Self-assembly 360 −38.8 21.41 to 52.28 Maintenance of stability and its anti-proliferative activities during in vitro gastrointestinal digestion (232)
Chitosan - β-Lactoglobulin Anthocyanin Ionic gelation 580.4 +49.6 77.4 Storage stability and oxidant stability during in vitro simulated digestion (233)
Zein–Carboxymethyl cellulose Quercetin and Resveratrol Antisolvent Precipitation 217 −33.6 to −45.6 25,1 Thermal stability and orally administered (234)

WPI, Whey Protein Isolate; WPC, Whey Protein Concentrate.