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. 1991 Jan;65(1):25–30. doi: 10.1136/hrt.65.1.25

Cardiac metabolism during exercise in healthy volunteers measured by 31P magnetic resonance spectroscopy

Michael A Conway 1, J David Bristow 1, Martin J Blackledge 1, Bheeshma Rajagopalan 1, George K Radda 1
PMCID: PMC1024458  PMID: 1993127

Abstract

A technique was devised for individuals to exercise prone in a magnet during magnetic resonance spectroscopy of the heart and phosphorus-31 magnetic resonance spectra of the heart were obtained by the phase modulated rotating frame imaging technique in six healthy volunteers during steady state dynamic quadriceps exercise. During prone exercise heart rate, blood pressure, and total body oxygen consumption were measured at increasing loads and the results were compared with those during Bruce protocol treadmill exercise. During prone exercise with a 5 kg load the heart rate was similar and the systolic and diastolic blood pressures were higher than those during stage 1 of the Bruce protocol. The rate-pressure products were similar but the total body oxygen consumption was lower during prone exercise. There was no difference in the ratio of phosphocreatine to adenosine triphosphate during rest and exercise.

Thus during exercise that produced a local cardiac stress equal to or greater than that during stage 1 of the Bruce protocol treadmill exercise, the energy requirements of the normal human myocardium were adequately supplied by oxidative phosphorylation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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