Table 5.
Baseline characteristics of participants in Study 2. Data are shown as the median and interquartile range (IQR) unless noted otherwise.
| Characteristics | Total (n=28) | Sequence | |||
|---|---|---|---|---|---|
| ABCD (n=7) | BCDA (n=7) | CDAB (n=7) | DABC (n=7) | ||
| Diabetes (n, %) | 13 (46.4%) | 4 (57.1%) | 4 (57.1%) | 2 (22.2%) | 3 (42.9%) |
| Male (n, %) | 9 (32.1%) | 2 (22.2%) | 3 (42.9%) | 2 (22.2%) | 2 (22.2%) |
| Age (years) | 43.0 (37.5, 51.0) | 47.0 (37.0, 58.0) | 41.0 (35.0, 46.0) | 44.0 (39.0, 46.0) | 42.0 (36.0, 57.0) |
| Height (cm) | 163.0 (157.3, 166.8) | 161.0 (158.0, 165.0) | 165.0 (155.0, 175.0) | 163.0 (157.0, 166.0) | 160.0 (154.0, 167.0) |
| Weight (kg) | 79.2 (71.6, 89.5) | 77.3 (68.9, 85.3) | 80.7 (74.4, 97.6) | 85.6 (68.3, 86.4) | 73.1 (66.6, 97.8) |
| BMI (kg/m2) | 30.3 (28.3, 32.2) | 30.5 (28.3, 32.5) | 30.0 (29.6, 32.6) | 31.4 (27.6, 32.3) | 30.1 (26.9, 32.0) |
| Waist circumference | 101.5 (97.0, 108.0) | 99.0 (87.0, 117.0) | 104.0 (101.0, 113.0) | 99.0 (93.0, 104.0) | 102.0 (93.0, 108.0) |
| Hip circumference | 111.0 (104.0, 115.8) | 112.0 (97.0, 119.0) | 112.0 (108.0, 115.0) | 110.0 (105.0, 117.0) | 107.0 (102.0, 115.0) |
| Waist-hip ratio | 0.92 (0.89, 0.96) | 0.93 (0.88, 0.98) | 0.94 (0.93, 0.99) | 0.89 (0.88, 0.93) | 0.91 (0.89, 1.02) |
| Systolic blood pressure (mmHg) | 135.0 (124.8, 144.3) | 134.0 (117.0, 145.0) | 139.0 (133.0, 148.0) | 136.0 (122.0, 150.0) | 134.0 (132.0, 142.0) |
| Diastolic blood pressure (mmHg) | 83.0 (69.3, 86.8) | 68.0 (62.0, 92.0) | 82.0 (78.0, 85.0) | 84.0 (73.0, 85.0) | 86.0 (68.0, 97.0) |
| Pulse (bpm) | 76.0 (68.0, 80.0) | 68.0 (64.0, 80.0) | 80.0 (76.0, 80.0) | 73.0 (60.0, 78.0) | 74.0 (70.0, 98.0) |
| Body fat (%) | 38.9 (31.9, 43.1) | 38.9 (32.8, 43.2) | 38.9 (31.3,42.3) | 39.9 (27.6, 43.5) | 37.9 (33.2, 42.8) |
| Laboratory investigations | |||||
| HbA1c (%) | 6.2 (5.7, 6.9) | 6.4 (5.9, 7.6) | 6.8 (5.7, 6.9) | 5.6 (5.3, 6.5) | 6.2 (6.1, 6.6) |
| Fasting plasma glucose (mg/dL) | 104.5 (87.0, 115.8) | 105.0 (93.0, 138.0) | 109.0 (92.0, 115.0) | 87.0 (82.0, 116.0) | 104.0 (85.0, 120.0) |
| Insulin (uU/mL) | 18.1 (11.9, 23.5) | 18.1 (11.9, 19.7) | 15.4 (13.9, 21.2) | 15.7 (8.8, 29.9) | 22.5 (13.4, 25.1) |
| hsCRP (mg/L) | 1.9 (1.0, 6.1) | 3.6 (1.1, 6.8) | 1.7 (1.1, 8.2) | 1.0 (0.5, 2.2) | 3.6 (1.8, 9.9) |
| Creatinine (mg/dL) | 0.67 (0.63, 0.85) | 0.66 (0.63, 0.83) | 0.75 (0.63, 0.87) | 0.66 (0.64, 0.81) | 0.70 (0.61, 1.00) |
| AST (U/L) | 18.5 (15.0, 30.8) | 15.0 (14.0, 22.0) | 22.0 (15.0, 37.0) | 18.0 (15.0, 55.0) | 19.0 (15.0, 31.0) |
| ALT (U/L) | 19.0 (14.0, 49.8) | 14.0 (13.0, 31.0) | 19.0 (14.0, 52.0) | 22.0 (18.0, 96.0) | 19.0 (9.0, 59.0) |
| Alkaline phosphatase (U/L) | 61.5 (55.0, 76.5) | 65.0 (63.0, 71.0) | 77.0 (43.0, 88.0) | 55.0 (50.0, 57.0) | 61.0 (55.0, 84.0) |
| Cholesterol (mg/dL) | 175.0 (146.0, 200.8) | 175.0 (141.0, 200.0) | 174.0 (144.0, 189.0) | 175.0 (134.0, 192.0) | 219.0 (160.0, 224.0) |
| HDL cholesterol (mg/dL) | 42.5 (35.3, 51.8) | 43.0 (35.0, 52.0) | 42.0 (36.0, 57.0) | 34.0 (34.0, 47.0) | 48.0 (41.0, 54.0) |
| LDL cholesterol (mg/dL) | 96.2 (81.0, 124.1) | 115.0 (66.4, 122.0) | 85.2 (67.0, 115.2) | 109.0 (82.6, 124.8) | 98.2 (80.8, 144.2) |
| Triglyceride (mg/dL) | 129.0 (82.0, 211.5) | 104.0 (85.0, 173.0) | 139.0 (75.0, 242.0) | 116.0 (81.0, 129.0) | 139.0 (71.0, 302.0) |