Table 1.
Prevalence and Interreader Agreement of Gradings that Identified RPD Based on Different Criteria when Evaluated on the Entire OCT Volume Scan or on a Selected B-Scan among the Cases (n = 100) Evaluated by 12 Readers
| Prevalence of Readings (%)∗ | Agreement Rate (%) | Gwet’s AC1 | |
|---|---|---|---|
| Presence on the Entire OCT Volume Scan | |||
| Any RPD lesion(s) | 84 | 80 | 0.72 |
| Any Stage 2 or 3 RPD lesion(s) | 83 | 79 | 0.71 |
| ≥ 5 Stage 2 or 3 RPD lesion(s) | 76 | 76 | 0.62 |
| Cluster of ≥ 5 definite RPD lesions on IR corresponding to Stage 2 or 3 lesions on OCT | 42 | 79 | 0.60 |
| Presence on Selected OCT B-scans | |||
| Any RPD lesion(s) | 80 | 77 | 0.65 |
| Any Stage 1 RPD lesion(s) | 51 | 54 | 0.08 |
| Any Stage 2 RPD lesion(s) | 74 | 73 | 0.56 |
| Any Stage 3 RPD lesion(s) | 28 | 87 | 0.79 |
| Any Stage 4 RPD lesion(s) | 1 | 99 | 0.99 |
| Any Stage 2 or 3 RPD lesion(s) | 77 | 76 | 0.63 |
| ≥ 5 Stage 2 or 3 RPD lesions | 32 | 76 | 0.58 |
AC1 = first-order coefficient; IR = infrared reflectance; RPD = reticular pseudodrusen.
∗
Proportion of the 1200 readings across 12 readers of the 100 cases considering RPD to be present based on the criteria evaluated.