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. 2023 May 24;14:1136089. doi: 10.3389/fendo.2023.1136089

Table 1.

Clinical characteristics of patients with bone metastasis of gastric cancer in train set and test set.

Group Overall Train Set Test Set
Mets_bone No Yes P-value No Yes P-value No Yes P-value
N N=22181 N=975 N=15544 N=668 N=6637 N=307
Age 65.3 (12.6) 62.0 (13.2) <0.001 65.3 (12.6) 62.0 (13.1) <0.001 65.2 (12.6) 61.9 (13.5) <0.001
Sex: 0.006 0.017 0.202
 Male 14114 (63.6%) 663 (68.0%) 9799 (63.0%) 452 (67.7%) 4315 (65.0%) 211 (68.7%)
 Female 8067 (36.4%) 312 (32.0%) 5745 (37.0%) 216 (32.3%) 2322 (35.0%) 96 (31.3%)
Race: 0.002 0.03 0.012
 White 15896 (71.7%) 739 (75.8%) 11104 (71.4%) 494 (74.0%) 4792 (72.2%) 245 (79.8%)
 Black 2884 (13.0%) 90 (9.23%) 2032 (13.1%) 64 (9.58%) 852 (12.8%) 26 (8.47%)
 Other 3401 (15.3%) 146 (15.0%) 2408 (15.5%) 110 (16.5%) 993 (15.0%) 36 (11.7%)
Marital_status: 0.382 0.474 0.641
 No 8484 (38.2%) 387 (39.7%) 6010 (38.7%) 268 (40.1%) 2474 (37.3%) 119 (38.8%)
 Yes 13697 (61.8%) 588 (60.3%) 9534 (61.3%) 400 (59.9%) 4163 (62.7%) 188 (61.2%)
Site: <0.001 <0.001 <0.001
 Other 11094 (50.0%) 485 (49.7%) 7762 (49.9%) 331 (49.6%) 3332 (50.2%) 154 (50.2%)
 Cardia 7183 (32.4%) 401 (41.1%) 5058 (32.5%) 279 (41.8%) 2125 (32.0%) 122 (39.7%)
 Gastric antrum 3904 (17.6%) 89 (9.13%) 2724 (17.5%) 58 (8.68%) 1180 (17.8%) 31 (10.1%)
Grade: <0.001 <0.001 <0.001
 I 2419 (10.9%) 13 (1.33%) 1713 (11.0%) 8 (1.20%) 706 (10.6%) 5 (1.63%)
 II 5920 (26.7%) 154 (15.8%) 4148 (26.7%) 119 (17.8%) 1772 (26.7%) 35 (11.4%)
 III 13275 (59.8%) 789 (80.9%) 9303 (59.8%) 528 (79.0%) 3972 (59.8%) 261 (85.0%)
 IV 567 (2.56%) 19 (1.95%) 380 (2.44%) 13 (1.95%) 187 (2.82%) 6 (1.95%)
AJCC_T: <0.001 <0.001 <0.001
 T1 5512 (24.9%) 187 (19.2%) 3915 (25.2%) 128 (19.2%) 1597 (24.1%) 59 (19.2%)
 T2 2642 (11.9%) 39 (4.00%) 1831 (11.8%) 27 (4.04%) 811 (12.2%) 12 (3.91%)
 T3 6074 (27.4%) 136 (13.9%) 4227 (27.2%) 100 (15.0%) 1847 (27.8%) 36 (11.7%)
 T4 7953 (35.9%) 613 (62.9%) 5571 (35.8%) 413 (61.8%) 2382 (35.9%) 200 (65.1%)
AJCC_N: <0.001 <0.001 0.001
 N1 16505 (74.4%) 725 (74.4%) 11581 (74.5%) 496 (74.3%) 4924 (74.2%) 229 (74.6%)
 N2 2124 (9.58%) 48 (4.92%) 1498 (9.64%) 36 (5.39%) 626 (9.43%) 12 (3.91%)
 N3 3552 (16.0%) 202 (20.7%) 2465 (15.9%) 136 (20.4%) 1087 (16.4%) 66 (21.5%)
Mets_brain: <0.001 <0.001 <0.001
 No 22078 (99.5%) 938 (96.2%) 15478 (99.6%) 640 (95.8%) 6600 (99.4%) 298 (97.1%)
 Yes 103 (0.46%) 37 (3.79%) 66 (0.42%) 28 (4.19%) 37 (0.56%) 9 (2.93%)
Mets_liver: <0.001 <0.001 <0.001
 No 19162 (86.4%) 622 (63.8%) 13428 (86.4%) 434 (65.0%) 5734 (86.4%) 188 (61.2%)
 Yes 3019 (13.6%) 353 (36.2%) 2116 (13.6%) 234 (35.0%) 903 (13.6%) 119 (38.8%)
Mets_lung: <0.001 <0.001 <0.001
 No 21305 (96.1%) 737 (75.6%) 14943 (96.1%) 508 (76.0%) 6362 (95.9%) 229 (74.6%)
 Yes 876 (3.95%) 238 (24.4%) 601 (3.87%) 160 (24.0%) 275 (4.14%) 78 (25.4%)