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. 2023 May 24;14:1136089. doi: 10.3389/fendo.2023.1136089

Table 3.

Patient clinical characteristics of gastric cancer with bone metastases in the train set and test set.

Group Overall Train set Test set
Status Alive Death P-value Alive Death P-value Alive Death P-value
N N=29 N=946 N=21 N=663 N=8 N=283
Age: 0.025 0.015 0.734
 No 19 (65.5%) 405 (42.8%) 15 (71.4%) 281 (42.4%) 4 (50.0%) 124 (43.8%)
 Yes 10 (34.5%) 541 (57.2%) 6 (28.6%) 382 (57.6%) 4 (50.0%) 159 (56.2%)
Sex: 0.929 1 0.716
 Male 19 (65.5%) 644 (68.1%) 14 (66.7%) 452 (68.2%) 5 (62.5%) 192 (67.8%)
 Female 10 (34.5%) 302 (31.9%) 7 (33.3%) 211 (31.8%) 3 (37.5%) 91 (32.2%)
Race: 0.004 0.015 0.26
 White 17 (58.6%) 722 (76.3%) 12 (57.1%) 516 (77.8%) 5 (62.5%) 206 (72.8%)
 Black 1 (3.45%) 89 (9.41%) 1 (4.76%) 58 (8.75%) 0 (0.00%) 31 (11.0%)
 Other 11 (37.9%) 135 (14.3%) 8 (38.1%) 89 (13.4%) 3 (37.5%) 46 (16.3%)
Marital_status: 0.124 0.145 0.718
 No 16 (55.2%) 371 (39.2%) 12 (57.1%) 258 (38.9%) 4 (50.0%) 113 (39.9%)
 Yes 13 (44.8%) 575 (60.8%) 9 (42.9%) 405 (61.1%) 4 (50.0%) 170 (60.1%)
Site: 0.126 0.112 0.394
 Other 18 (62.1%) 467 (49.4%) 12 (57.1%) 331 (49.9%) 6 (75.0%) 136 (48.1%)
 Cardia 7 (24.1%) 394 (41.6%) 5 (23.8%) 274 (41.3%) 2 (25.0%) 120 (42.4%)
 Gastric antrum 4 (13.8%) 85 (8.99%) 4 (19.0%) 58 (8.75%) 0 (0.00%) 27 (9.54%)
Grade: 0.649 0.771 0.234
 I 0 (0.00%) 13 (1.37%) 0 (0.00%) 7 (1.06%) 0 (0.00%) 6 (2.12%)
 II 3 (10.3%) 151 (16.0%) 2 (9.52%) 108 (16.3%) 1 (12.5%) 43 (15.2%)
 III 25 (86.2%) 764 (80.8%) 19 (90.5%) 534 (80.5%) 6 (75.0%) 230 (81.3%)
 IV 1 (3.45%) 18 (1.90%) 0 (0.00%) 14 (2.11%) 1 (12.5%) 4 (1.41%)
AJCC_T: 0.715 0.561 0.621
 T1 6 (20.7%) 181 (19.1%) 4 (19.0%) 117 (17.6%) 2 (25.0%) 64 (22.6%)
 T2 2 (6.90%) 37 (3.91%) 2 (9.52%) 29 (4.37%) 0 (0.00%) 8 (2.83%)
 T3 4 (13.8%) 132 (14.0%) 2 (9.52%) 91 (13.7%) 2 (25.0%) 41 (14.5%)
 T4 17 (58.6%) 596 (63.0%) 13 (61.9%) 426 (64.3%) 4 (50.0%) 170 (60.1%)
N: 0.345 0.149 1
 N1 25 (86.2%) 700 (74.0%) 19 (90.5%) 498 (75.1%) 6 (75.0%) 202 (71.4%)
 N2 1 (3.45%) 47 (4.97%) 1 (4.76%) 27 (4.07%) 0 (0.00%) 20 (7.07%)
 N3 3 (10.3%) 199 (21.0%) 1 (4.76%) 138 (20.8%) 2 (25.0%) 61 (21.6%)
Surgery: 1 0.616 1
 No 28 (96.6%) 907 (95.9%) 20 (95.2%) 634 (95.6%) 8 (100%) 273 (96.5%)
 Yes 1 (3.45%) 39 (4.12%) 1 (4.76%) 29 (4.37%) 0 (0.00%) 10 (3.53%)
Radiation: 0.538 0.142 0.254
 No 22 (75.9%) 650 (68.7%) 18 (85.7%) 452 (68.2%) 4 (50.0%) 198 (70.0%)
 Yes 7 (24.1%) 296 (31.3%) 3 (14.3%) 211 (31.8%) 4 (50.0%) 85 (30.0%)
Chemotherapy: 0.902 0.573 0.715
 No 12 (41.4%) 364 (38.5%) 10 (47.6%) 259 (39.1%) 2 (25.0%) 105 (37.1%)
 Yes 17 (58.6%) 582 (61.5%) 11 (52.4%) 404 (60.9%) 6 (75.0%) 178 (62.9%)
Mets_brain: 1 1 0.309
 No 28 (96.6%) 910 (96.2%) 21 (100%) 639 (96.4%) 7 (87.5%) 271 (95.8%)
 Yes 1 (3.45%) 36 (3.81%) 0 (0.00%) 24 (3.62%) 1 (12.5%) 12 (4.24%)
Mets_liver: 0.433 0.33 1
 No 21 (72.4%) 601 (63.5%) 16 (76.2%) 420 (63.3%) 5 (62.5%) 181 (64.0%)
 Yes 8 (27.6%) 345 (36.5%) 5 (23.8%) 243 (36.7%) 3 (37.5%) 102 (36.0%)
Mets_lung: 1 0.793 0.429
 No 22 (75.9%) 715 (75.6%) 17 (81.0%) 504 (76.0%) 5 (62.5%) 211 (74.6%)
 Yes 7 (24.1%) 231 (24.4%) 4 (19.0%) 159 (24.0%) 3 (37.5%) 72 (25.4%)
Survival_months 26.1 (31.4) 6.20 (8.10) 0.002 29.0 (33.3) 6.30 (8.29) 0.005 18.8 (26.0) 5.98 (7.64) 0.208