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. 2023 May 24;14:1136089. doi: 10.3389/fendo.2023.1136089

Table 4.

Univariate and multivariate cox analysis of OS in patients with bone metastases from gastric cancer.

Univariate Analysis Multivariate Analysis
HR 95%CI P-value HR 95%CI P-value
Age >60
 No ref ref
 Yes 1.114 0.980 -1.268 0.099
Sex
 Male ref ref
 Female 1.031 0.899-1.182 0.659
Marital_status
 No ref ref
 Yes 0.910 0.798-1.037 0.156
Site
 Other ref ref ref ref
 Cardia 0.845 0.739-0.966 0.014 0.914 0.797-1.050 0.203
Gastric antrum 1.083 0.859-1.364 0.501 1.155 0.915-1.4550 0.226
Grade
 I ref ref
 II 0.792 0.449-1.396 0.420
 III 1.014 0.586-1.754 0.962
 IV 1.021 0.500-2.083 0.955
AJCC_T
 T1 ref ref ref ref
 T2 0.666 0.467-0.9487 0.024 0.633 0.443-0.903 0.012
 T3 0.848 0.677-1.0613 0.150 1.008 0.820-1.267 0.947
 T4 1.094 0.926-1.2917 0.293 1.081 0.915-1.278 0.359
AJCC_N
 N1 ref ref
 N2 0.866 0.644-1.164 0.342
 N3 1.165 0.995-1.364 0.058
Surgery
 No ref ref ref ref
 Yes 0.658 0.477-0.9073 0.011 0.512 0.369-0.711 <0.001
Radiation
 No ref ref ref ref
 Yes 0.870 0.758-0.9976 0.046 0.967 0.840-1.114 0.644
Chemotherapy
 No ref ref ref ref
 Yes 0.280 0.244-0.322 <0.001 0.268 0.233-0.309 <0.001
Mets_brain
 No ref ref
 Yes 1.016 0.728-1.42 0.927
Mets_liver
 No ref ref
 Yes 0.9989 0.875-1.141 0.986
Mets_lung
 No ref ref
 Yes 1.093 0.942-1.268 0.242