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Quality control of the radiolabeled sdAb conjugates. A: SDS-PAGE and phosphor imaging of iso-[131l]GMIB-PODS-5F7GGC (a), [125I]MEGMIB-5F7GGC (b), iso-[211At]AGMB-PODS-5F7GGC (c) and [177Lu]Lu-DOTA-PODS-5F7GGC (d); B: binding affinity of iso-[131l]GMIB-PODS-5F7GGC measured in BT474 cells; C: binding affinity of iso-[131l]GMIB-PODS-5F7GGC measured in SKOV-3 cells; D: binding affinity of/’so-[211At]AGMB-PODS-5F7GGC measured in BT474 cells.
