Figure 3.

Schematic depiction of the effect of altered Abl kinase activity on the distribution of actin in TSM1. Organization of growth cone actin into domains (highly cross-linked subnetworks; see text) is indicated by separated ovals (compare figure 1b). In Abl overexpression, these tend to spread out over a larger region; in Abl knockdown they tend to condense, and often form dense puncta.