Table 3.

Clinical correlation of TMPRSS2 expression with age, sex, nuclear AhR, IL18, and overall stage in 25 lung cancer patients ^a .

Characteristics	TMPRSS2 High b (N = 17)	TMPRSS2 Low c (N = 8)	P‐value
Age (years)
≤ 60	4	2	1
> 60	13	6
Gender
Female	11	1	0.03 d
Male	6	7
Nuclear AhR expression
High e	11	0	0.0029 d
Low f	6	8
IL18 expression
High e	15	3	0.0169 d
Low f	2	5
Overall stage
III–IV	10	1	0.04 d
I–II	7	7

^a By Fisher's test.

^b High: Representative lung adenocarcinoma with intense TMPRSS2 immunoreactivity (+: score 2,3).

^c Low: Representative lung adenocarcinoma showing no or weak TMPRSS2 immunoreactivity (−: scores 0, 1).

^d P < 0.05.

^e High: Representative lung adenocarcinoma with intense nuclear AhR or IL18 immunoreactivity (+: scores 2, 3).

^f Low: Representative lung adenocarcinoma showing no or weak nuclear AhR or IL18 immunoreactivity (−: scores 0, 1).