Table 1.
Study characteristics of Ilizarov and LRS group.
| ILIZAROV DATA | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Author (year) | Study design | Sample size (n) | M/F (n) | Age (year) | Site of Intervention (N) | MPSP (n) | Mean bone defects (cm) | Technique/Procedure | Mean follow up (month) | MCMS |
| V Barbarossa (2001) | Prospective | 30 | 24/6 | 39.4± 14.4 (25–80) | Femur | 4.4 ± NS | 6.3 ± NS | Ilizarov | NS (24–126) | 66 |
| David W. Sanders (2002) | retrospective | 19 | 12/3 (1 loss of f/u and 3 amputated NS) | 45 ± NS (20–78) | Tibia | NS | 8 ± NS (4.5–12) | Ilizarov | 39 ± NS | 50 |
| S Patil (2006) | Retrospective | 41 | 35/5 | 41 ± NS (10–73) | 36 Tibia 5 Femur | 3 ± NS (1–10) | NS | Ilizarov | 61.1 ± NS | 66 |
| A Krishnan (2006) | Retrospective | 20 | 17/3 | 38.4 ± NS (18–65) | Femur | 4.4±2 (1–9) | NS | Ilizarov | 62.8±25 | 54 |
| MP Magadum (2006) | Retrospective | 27 | 27/0 | 39±14 (15–65) | Tibia | 2 ± NS (1–4) | NS | Ilizarov | 27 ± NS (25–39) | 58 |
| Dror Paley (2006) | Retrospective | 21 | 12/9 | 40 ± NS (12–63) | Tibia | NS | NS | Ilizarov | 83.4 ± NS (26–144) | 63 |
| Ranjit Baruah (2007) | Retrospective | 50 | 45/5 | NS (18–56) | Tibia | NS | 3.5 ± NS (2–9) | Ilizarov | NS (24–72) | 59 |
| M. Trigui (2008) | Retrospective | 9 | 5/4 | 20 ± NS | 8 Tibia 1 Femur |
NS | 4.1 ± NS (2–8) | Ilizarov | 28 ± NS | 53 |
| Khaled M Emara (2008) | Prospective | 33 | 22/11 | 2 ± NS | Tibia | NS | 6 ± NS | Ilizarov | 36 ± NS (22–48) | 68 |
| S. Robert Rozbruch (2008) | Retrospective | 38 | 30/8 | 43 ± NS (8−72) | Tibia | 4 ± NS (0−20) | 5.9 ± NS (1.5–16) | Ilizarov | 37 ± NS (15–63) | 58 |
| Michael D. Mckee (2008) | Retrospective | 11 | 8/3 | 43.7 ± NS (30–71) | Tibia | 4.5 ± NS (2–12) | NS | Ilizarov | 41 ± NS (24–82) | 56 |
| Francesco Sala (2011) | Retrospective | 12 | 8/4 | 44 ± NS (19–79) | Tibial | 4.66 ± NS | 8.06±2.6 (3.0–12.0) | Ilizarov | 24.6±4.7 (18–32) | 50 |
| M Sayed (2013) | Retrospective | 20 | 19/1 | 37.45 ± NS | Femur | 1.95±1.05 (1–5) | NS | Ilizarov | 36.65±15.8 (25–82) | 62 |
| P Yin (2014) | Retrospective | 66 | 62/4 | 37.06 ± NS | Tibia | NS | 6.27 ± NS (3–13) | Ilizarov | 25.91 ± NS | 63 |
| Chang Seon Oh (2015) | Retrospective | 7 | 6/1 | 14.4 ± NS (4.8–36.9) | 5 Tibia 2 Femur | NS | 7.3 ± NS (5.1–12.1) | Ilizarov | 106.2 ± NS | 59 |
| Peng Yin (2015) | Retrospective | 72 | 92/18 | 38.90 ± NS | Tibias | 2.61 ± NS (1–8) | 6.15 ± NS (3−13) | Ilizarov | 23.12 ± NS (14–46) | 60 |
| Ramji Lal Sahu (2016) | Prospective | 60 | 50/10 | 37.5 ± NS (25–45) | Tibia | 3.5 ± NS (2–5) | 3 ± NS (2–5) | Ilizarov | 36 ± NS (26–50) | 71 |
| Kemal Aktuglu (2016) | Retrospective | 24 | 21/3 | 35.04±17.19 (8–69) | Tibia | 3.64±2.66 (range, 0–11). | 7.01±2.88 (5–18) | Ilizarov | 74.08±24.17 | 53 |
| R Rohilla (2016) | Prospective | 35 | 32/3 | 33.2 ± NS (18–64) | Tibia | 1 ± NS | 5.84 ± NS (3–9) | I-Ilizarov | 33.8 ± NS | 79 |
| Martin McNally (2017) | Prospective | 79 | 61/18 | 43.0 ± NS | Tibia | 2.2 ± NS (1–5) | 4.93 ± NS | Ilizarov | 40.8 ± NS (6–131) | 71 |
| Gamal Ahmed Hosny (2018) | Retrospective | 144 | 87/57 | 44.48 ± NS | 18 Humerus | 4.35±1.21 (2–6) | 5.98 ± NS (3−10) | Ilizarov | 51.05 ± NS | 60 |
| 52 Femur | ||||||||||
| 74 Tibia | ||||||||||
| K Bhowmick (2018) | Retrospective | 8 | 7/1 | 41 ± NS (22–57) | Tibia | All 8 underwent 1 procedure | NS | Ilizarov | 33±35.05 (12–20) | 62 |
| S Fahad (2019) | Retrospective | 51 | 41/10 | 45.65±16.69 | Tibia | 2 ± NS (1–4) | 3.5 ± NS (2–5) | Ilizarov | 36.84 ± NS | 69 |
| G Testa (2020) | Retrospective | 26 | 20/6 | 51.3±15.3 (22–68) | Tibia | All 26 underwent 1 procedure | NS | Ilizarov | 28.25 ± NS (9–42.75) | 62 |
| I Sigmund (2020) | Prospective | 47 ASR: 20, BT: 27 | NS | ASR: 48.9 ± NS (21–78), | Tibia | ASR: 2.9 ± NS (1–5) | ASR: 4.0 ± NS (2–5) | Ilizarov | 37.9 ± NS (16–128) | 79 |
| NS | BT: 50.9 ± NS (29–75), | BT: 2.7 ± NS (1–6) | BT: 5.9 ± NS (3–10) | |||||||
| R K Baruah (2020) | Retrospective | 86 | 72/24 | NS (18–65) | Tibia | 5 ± NS | 5.04 ± NS (3–9) | Ilizarov | 24 ± NS | 69 |
| Gamal Ahmed Hosny (2020) | Retrospective | 13 | 11/2 | 9.1 ± NS (2–14.5) | Femur | 3.3 ± NS | NS | Ilizarov | 60.15 ± NS | 65 |
| A Chalak (2021) | Retrospective | 30 | 16/14 | 39.27 ± NS (10–66), | Tibia | 16 underwent 1 procedure | 7.17 ± NS (2–12) | Ilizarov | 39.36 ± NS (24–54) | 69 |
| Lukasz Szelereski (2021) | Retrospective | 102 | 76/26 | 46.7 ± NS (11–84) | Tibia | NS | NS | Ilizarov | 84 ± NS (24–144) | 65 |
| LRS DATA | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Author (year) | Study design | Sample size (n) | M/F (n) | Age (year) | Site of intervention (n) | MPSP (n) | Mean bone defects (cm) | Technique/Procedure | Mean follow up (month) | MCMS |
| Hiranaya Seenappa (2013) | Prospective | 30 | 28/2 | 29.28 ± NS (19–66) | 16 Tibia, | 2.67 ± NS (0–10) | 5.06 ± NS (1–10) | LRS | 27 ± NS (14–41) | 66 |
| 10 Femur, | ||||||||||
| 4 Humerus | ||||||||||
| Peng Yin (2015) | Retrospective | 38 | 92/18 | 38.90 ± NS | Femur | 2.61 ± NS (1–8) | 6.15 ± NS (3−13) | Monorail | 23.12 ± NS (14–46) | 60 |
| R Rohilla (2016) | Prospective | 35 | 30/5 | 29.3 ± NS (18–65) | Tibia | 1 ± NS | 5.78 ± NS (3–10) | LRS | 32.6 ± NS | 79 |
| Qun Jhang (2017) | Retrospective | 41 | 31/10 | 44 ± NS (26–76) | Femur | NS | 10.1 ± NS (6–17) | LRS | 35 ± NS (20–60) | 61 |
| S Gupta (2018) | Retrospective | 14 | 13/1 | 38.1 ± NS | Tibia | NS | 6.4±1.3 | LRS | 33.2 ± NS (24–50) | 60 |
| Xun Chen (2019) | Prospective | 23 | 19/4 | 37.8 ± NS (19–54) | Tibia | 2.5 ± NS (2–4) | 6.5 ± NS (5.2–8.1) | LRS | 57.6 ± NS (36–72) | 62 |
| N Kushwaha (2020) | Prospective | 21 | 19/2 | 29.43±14.07 | Tibia | NS | NS | LRS | 29.5 ± NS (16–50) | 76 |
| Victor Lu (2021) | Retrospective | 8 | 8/0 | 37.75 ± NS | femur | 4.5 ± NS | 9.69 ± NS | Rail Fixator | 57 ± NS | 50 |
ASR, Acute Shortening and Relengthening; BT, Bone Transport; MPSP, Mean previous surgical procedures; MCMS, Modified Coleman Methodology score; NS, Not Specified; LRS, Limb Reconstruction System.