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. 2023 May 25;9(6):e16665. doi: 10.1016/j.heliyon.2023.e16665

Table 3.

Influence of TCZ in comparison with other treatment groups.

Anti-inflammatory treatment
p-value
TCZ Anti-TNF JAK-i Other
Age (years), median (IQR) 75.28 (65.3–85.24) 45.79 (31.93–64.06) 64.01 (51.66–81.16) 62.1 (56.17–79.63) <0.001
Male 35.7% 49.0% 22.7% 28.9% 0.006
Diagnosis of infectious disease on admission 50.0% 22.4% 38.1% 26.7% 0.040
CRP (mg/dL), median (IQR) 0.5 (0.05–21.21) 24.09 (6.54–91.81) 19.64 (6.65–76.71) 93.32 (16.95–172.16) <0.001
WBC (K/μL), median (IQR), 9.25 (6.4–11.53) 8.6 (6.4–11.1) 7.45 (5.08–9.88) 7.8 (5.95–12.95) 0.315

TCZ - Tocilizumab; TNF - Tumor necrosis factor; JAK - Janus kinase inhibitors; CRP - C-reactive protein; WBC - White blood cells.