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. Author manuscript; available in PMC: 2023 Jun 7.
Published in final edited form as: N Engl J Med. 2022 Jun 16;386(24):2283–2294. doi: 10.1056/NEJMoa2110339

Figure 3. Detection of CHAPV by an Indirect Immunofluorescence Assay and Electron Microscopy.

Figure 3.

In Panel A, an indirect immunofluorescence assay shows CHAPV Bolivia 2019 isolate obtained from Patient S1-2 (passage 1 in Vero E6 cells, 7 days after inoculation). In Panel B, electron microscopy of CHAPV Bolivia 2019 isolate shows typical arenavirus morphologic features with pleomorphic virions containing ribosomes. The virus isolate was obtained from Patient S1-4 (passage 2 in Vero E6 cells, 7 days after inoculation). The arrow indicates a budding viral particle. The scale bar represents 200 nm.